48,588
edits
Difference between revisions of "Cystitis glandularis"
Jump to navigation
Jump to search
no edit summary
(split out) |
|||
| (13 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Cystitis cystica et glandularis - alt -- intermed mag.jpg | |||
| Width = | |||
| Caption = Cystitis glandularis. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = nests of urothelium within the lamina propria with cyst formation; lining cells are glandular (cuboidal and/or columnar epithelium); +/-goblet cells; nests should '''not''' extend into the muscularis propria | |||
| Subtypes = | |||
| LMDDx = [[cystitis cystica]], [[nested variant of urothelial carcinoma]], [[tubular adenoma of the urinary bladder]], [[adenocarcinoma in situ of the urinary bladder]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Staging = | |||
| Site = [[urinary bladder]] - see ''[[urothelium]]'' | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
{{ Infobox external links | {{ Infobox external links | ||
| Name = Cystitis | | Name = Cystitis glandularis | ||
| EHVSC = 10173 | | EHVSC = 10173 | ||
| pathprotocols = | | pathprotocols = | ||
| Line 6: | Line 38: | ||
| pathoutlines = | | pathoutlines = | ||
}} | }} | ||
'''Cystitis glandularis''' is an uncommon type of inflammatory process that afflicts the [[urinary bladder]] ([[ | '''Cystitis glandularis''' is an uncommon type of inflammatory process that afflicts the [[urinary bladder]] ([[Cystitis|cystitis]]). | ||
''Cystitis cystica et glandularis'' and ''pyelitis cystica et glandularis'' redirect to here. | ''Cystitis cystica et glandularis'' and ''pyelitis cystica et glandularis'' redirect to here. | ||
==General== | ==General== | ||
*Benign.<ref name=pmid25202387>{{Cite journal | last1 = Yi | first1 = X. | last2 = Lu | first2 = H. | last3 = Wu | first3 = Y. | last4 = Shen | first4 = Y. | last5 = Meng | first5 = Q. | last6 = Cheng | first6 = J. | last7 = Tang | first7 = Y. | last8 = Wu | first8 = F. | last9 = Ou | first9 = R. | title = Cystitis glandularis: A controversial premalignant lesion. | journal = Oncol Lett | volume = 8 | issue = 4 | pages = 1662-1664 | month = Oct | year = 2014 | doi = 10.3892/ol.2014.2360 | PMID = 25202387 }}</ref> | *Benign.<ref name=pmid25202387>{{Cite journal | last1 = Yi | first1 = X. | last2 = Lu | first2 = H. | last3 = Wu | first3 = Y. | last4 = Shen | first4 = Y. | last5 = Meng | first5 = Q. | last6 = Cheng | first6 = J. | last7 = Tang | first7 = Y. | last8 = Wu | first8 = F. | last9 = Ou | first9 = R. | title = Cystitis glandularis: A controversial premalignant lesion. | journal = Oncol Lett | volume = 8 | issue = 4 | pages = 1662-1664 | month = Oct | year = 2014 | doi = 10.3892/ol.2014.2360 | PMID = 25202387 }}</ref> | ||
**No increased risk of malignancy on follow-up in an older paper with a cohort of 136 patients.<ref name=pmid18455631>{{cite journal |authors=Smith AK, Hansel DE, Jones JS |title=Role of cystitis cystica et glandularis and intestinal metaplasia in development of bladder carcinoma |journal=Urology |volume=71 |issue=5 |pages=915–8 |date=May 2008 |pmid=18455631 |doi=10.1016/j.urology.2007.11.079 |url=}}</ref> | |||
**An older series of 53 patients with intestinal metaplasia suggests it is not a significant risk for cancer.<ref>{{cite journal |authors=Corica FA, Husmann DA, Churchill BM, Young RH, Pacelli A, Lopez-Beltran A, Bostwick DG |title=Intestinal metaplasia is not a strong risk factor for bladder cancer: study of 53 cases with long-term follow-up |journal=Urology |volume=50 |issue=3 |pages=427–31 |date=September 1997 |pmid=9301710 |doi=10.1016/S0090-4295(97)00294-X |url=}}</ref> | |||
*Can be thought of as [[cystitis cystica]] with mucin-secreting cells lining the cystic spaces.<ref name=Ref_WMSP304>{{Ref WMSP|304}}</ref> | *Can be thought of as [[cystitis cystica]] with mucin-secreting cells lining the cystic spaces.<ref name=Ref_WMSP304>{{Ref WMSP|304}}</ref> | ||
*When seen in conjunction with ''cystitis cystica'' it is called ''cystitis cystica et glandularis''. | *When seen in conjunction with ''cystitis cystica'' it is called ''cystitis cystica et glandularis''. | ||
| Line 26: | Line 60: | ||
Note: | Note: | ||
*Nests should '''not''' extend into the muscularis propria. | *Nests should '''not''' extend into the muscularis propria. | ||
DDx: | |||
*[[Cystitis cystica]]. | |||
*[[Nested variant of urothelial carcinoma]]. | |||
*[[Tubular adenoma of the urinary bladder]]. | |||
*[[Adenocarcinoma in situ of the urinary bladder]]. | |||
===Images=== | ===Images=== | ||
| Line 39: | Line 79: | ||
==Sign out== | ==Sign out== | ||
<pre> | |||
Urinary Bladder Lesion, Transurethral Resection: | |||
- Cystitis cystica et cystica glandularis. | |||
- NEGATIVE for dysplasia and NEGATIVE for malignancy. | |||
</pre> | |||
===Block letters=== | |||
<pre> | <pre> | ||
URINARY BLADDER NECK, BIOPSY: | URINARY BLADDER NECK, BIOPSY: | ||
| Line 50: | Line 97: | ||
==See also== | ==See also== | ||
*[[Urothelium]]. | *[[Urothelium]]. | ||
*[[Intestinal metaplasia]]. | |||
==References== | ==References== | ||