Difference between revisions of "DNA sequence comparison"

From Libre Pathology
Jump to navigation Jump to search
 
(2 intermediate revisions by 2 users not shown)
Line 1: Line 1:
'''DNA sequence comparison''' is component of [[molecular pathology]].
'''DNA sequence comparison''' is component of [[molecular pathology]].


''DNA sequencing'' redirect here.
==Nomenclature==
==Nomenclature==
This is still somewhat in flux.<ref name=pmid17251329>{{cite journal |author=Ogino S, Gulley ML, den Dunnen JT, Wilson RB |title=Standard mutation nomenclature in molecular diagnostics: practical and educational challenges |journal=J Mol Diagn |volume=9 |issue=1 |pages=1–6 |year=2007 |month=February |pmid=17251329 |pmc=1867422 |doi=10.2353/jmoldx.2007.060081 |url=http://moldiag.highwire.org/cgi/content/full/9/1/1#B6}}</ref>
This is still somewhat in flux.<ref name=pmid17251329>{{cite journal |author=Ogino S, Gulley ML, den Dunnen JT, Wilson RB |title=Standard mutation nomenclature in molecular diagnostics: practical and educational challenges |journal=J Mol Diagn |volume=9 |issue=1 |pages=1–6 |year=2007 |month=February |pmid=17251329 |pmc=1867422 |doi=10.2353/jmoldx.2007.060081 |url=http://moldiag.highwire.org/cgi/content/full/9/1/1#B6}}</ref>
==Data format==
'''FASTA''': This contains just DNA sequence. The first line starts with '>' and contains the record name.
'''FASTQ''': This contains DNA sequence data with quality scores: The quality scores are indicated by defined characters.


==Basic local alignment search tool==
==Basic local alignment search tool==
Line 17: Line 23:
*[[Channelopathies]].
*[[Channelopathies]].
*[[Decendent identification]].
*[[Decendent identification]].
*[[Next generation sequencing]].


==References==
==References==

Latest revision as of 19:39, 11 October 2023

DNA sequence comparison is component of molecular pathology.

DNA sequencing redirect here.

Nomenclature

This is still somewhat in flux.[1]

Data format

FASTA: This contains just DNA sequence. The first line starts with '>' and contains the record name.

FASTQ: This contains DNA sequence data with quality scores: The quality scores are indicated by defined characters.

Basic local alignment search tool

Using BLAST

  1. Go to BLAST web site ( http://blast.ncbi.nlm.nih.gov/Blast.cgi ).
  2. Enter sequence.
  3. Enter consensus sequence (can be found with OMIM).
  4. Hit enter.

See also

References

External links