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| Subtypes = | | Subtypes = | ||
| LMDDx = [[squamous dysplasia of the esophagus]] | | LMDDx = [[squamous dysplasia of the esophagus]] | ||
| Stains = CK5/6 +ve | | Stains = | ||
| IHC = p63 +'ve, CK5/6 +'ve | |||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
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| Gross = | | Gross = | ||
| Grossing = | | Grossing = | ||
| Site = [[esophagus]] - proximal or mid portion | | Site = [[esophagus]] - usually proximal or mid portion | ||
| Assdx = [[squamous dysplasia of the esophagus]], [[alcohol]], [[smoking]] | | Assdx = [[squamous dysplasia of the esophagus]], [[alcohol]], [[smoking]] | ||
| Syndromes = | | Syndromes = | ||
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| Other = | | Other = | ||
| ClinDDx = benign [[esophageal stricture]] | | ClinDDx = benign [[esophageal stricture]] | ||
| Tx = usu. surgery - if feasible | | Tx = usu. surgery - if feasible, chemotherapy, radiation | ||
}} | }} | ||
'''Squamous cell carcinoma of the esophagus''' is a relatively uncommon form of esophageal cancer. | '''Squamous cell carcinoma of the esophagus''' is a relatively uncommon form of esophageal cancer. | ||
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==Microscopic== | ==Microscopic== | ||
Features - atypical squamous cells with | Features - atypical squamous cells with invasion through the basement membrane: | ||
*Cytology: | *Cytology: | ||
**Nucleus - typical central. | **Nucleus - typical central. | ||
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*[[Squamous dysplasia of the esophagus]]. | *[[Squamous dysplasia of the esophagus]]. | ||
*[[Adenocarcinoma of the esophagus]]. | *[[Adenocarcinoma of the esophagus]]. | ||
*[[metastasis|Metastatic]] carcinoma. | |||
===Images=== | ===Images=== |
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