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Difference between revisions of "Psammoma bodies"
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[[Image:Serous carcinoma - omentum -- very high mag.jpg| | [[Image:Serous carcinoma - omentum -- very high mag.jpg|300px|thumb|Psammoma bodies in [[serous carcinoma]]. [[H&E stain]].]] | ||
[[Image:Meningioma showing Psammoma body.jpg| | [[Image:Meningioma showing Psammoma body.jpg|300px|thumb|Psammoma bodies in [[meningioma]]. [[H&E stain]].]] | ||
'''Psammoma bodies''' appear in benign and malignant conditions. Their presence can help focus the DDx.<ref>{{Cite journal | last1 = Parwani | first1 = AV. | last2 = Chan | first2 = TY. | last3 = Ali | first3 = SZ. | title = Significance of psammoma bodies in serous cavity fluid: a cytopathologic analysis. | journal = Cancer | volume = 102 | issue = 2 | pages = 87-91 | month = Apr | year = 2004 | doi = 10.1002/cncr.20161 | PMID = 15098252 | URL = http://onlinelibrary.wiley.com/doi/10.1002/cncr.20161/full}}</ref> | '''Psammoma bodies''' appear in benign and malignant conditions. Their presence can help focus the DDx.<ref>{{Cite journal | last1 = Parwani | first1 = AV. | last2 = Chan | first2 = TY. | last3 = Ali | first3 = SZ. | title = Significance of psammoma bodies in serous cavity fluid: a cytopathologic analysis. | journal = Cancer | volume = 102 | issue = 2 | pages = 87-91 | month = Apr | year = 2004 | doi = 10.1002/cncr.20161 | PMID = 15098252 | URL = http://onlinelibrary.wiley.com/doi/10.1002/cncr.20161/full}}</ref> | ||
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===Benign=== | ===Benign=== | ||
*[[Endosalpingiosis]]. | *[[Endosalpingiosis]]. | ||
*[[Endometriosis]].<ref name=pmid8725135>{{Cite journal | last1 = Minkowitz | first1 = G. | title = Psammoma bodies in endometriosis: clinical, cytological, and physiopathological implications. | journal = Diagn Cytopathol | volume = 14 | issue = 4 | pages = 331-3 | month = Jun | year = 1996 | doi = 10.1002/(SICI)1097-0339(199605)14:4<331::AID-DC11>3.0.CO;2-L | PMID = 8725135 }}</ref><ref name=pmid15098252>{{Cite journal | last1 = Parwani | first1 = AV. | last2 = Chan | first2 = TY. | last3 = Ali | first3 = SZ. | title = Significance of psammoma bodies in serous cavity fluid: a cytopathologic analysis. | journal = Cancer | volume = 102 | issue = 2 | pages = 87-91 | month = Apr | year = 2004 | doi = 10.1002/cncr.20161 | PMID = 15098252 }}</ref> | |||
*[[Intrauterine device]] (IUD).<ref name=pmid12278909>{{Cite journal | last1 = Boon | first1 = ME. | last2 = Kirk | first2 = RS. | last3 = De Graaff Guilloud | first3 = JC. | title = Psammoma bodies and some opportunistic infections detected in cervical smears of women fitted with an IUD. | journal = Contracept Deliv Syst | volume = 2 | issue = 3 | pages = 231-6 | month = Jul | year = 1981 | doi = | PMID = 12278909 }}</ref> | *[[Intrauterine device]] (IUD).<ref name=pmid12278909>{{Cite journal | last1 = Boon | first1 = ME. | last2 = Kirk | first2 = RS. | last3 = De Graaff Guilloud | first3 = JC. | title = Psammoma bodies and some opportunistic infections detected in cervical smears of women fitted with an IUD. | journal = Contracept Deliv Syst | volume = 2 | issue = 3 | pages = 231-6 | month = Jul | year = 1981 | doi = | PMID = 12278909 }}</ref> | ||
*[[Endometrial polyp]].<ref name=pmid11854631>{{cite journal |author=Fausett MB, Zahn CM, Kendall BS, Barth WH |title=The significance of psammoma bodies that are found incidentally during endometrial biopsy |journal=Am. J. Obstet. Gynecol. |volume=186 |issue=2 |pages=180–3 |year=2002 |month=February |pmid=11854631 |doi= |url=}}</ref> | *[[Endometrial polyp]].<ref name=pmid11854631>{{cite journal |author=Fausett MB, Zahn CM, Kendall BS, Barth WH |title=The significance of psammoma bodies that are found incidentally during endometrial biopsy |journal=Am. J. Obstet. Gynecol. |volume=186 |issue=2 |pages=180–3 |year=2002 |month=February |pmid=11854631 |doi= |url=}}</ref> | ||
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*Anaplastic [[Meningioma]].<ref>{{Cite journal | last1 = KEPES | first1 = J. | title = Observations on the formation of psammoma bodies and pseudopsammoma bodies in meningiomas. | journal = J Neuropathol Exp Neurol | volume = 20 | issue = | pages = 255-62 | month = Apr | year = 1961 | doi = | PMID = 13752577 }}</ref> | *Anaplastic [[Meningioma]].<ref>{{Cite journal | last1 = KEPES | first1 = J. | title = Observations on the formation of psammoma bodies and pseudopsammoma bodies in meningiomas. | journal = J Neuropathol Exp Neurol | volume = 20 | issue = | pages = 255-62 | month = Apr | year = 1961 | doi = | PMID = 13752577 }}</ref> | ||
*[[Mesothelioma]]. | *[[Mesothelioma]]. | ||
*[[Biphasic hyalinizing psammomatous renal cell carcinoma]]. | |||
Memory device ''PSaMMoma'': '''P'''apillary (thyroid, renal), '''S'''erous (ovary), '''M'''eningioma, '''M'''esothelioma.<ref>URL: [http://ome.umaryland.edu/AcademicD/practiceExams/path/path_findings.html http://ome.umaryland.edu/AcademicD/practiceExams/path/path_findings.html]. Accessed on: 15 January 2012.</ref> | Memory device for common tumours ''PSaMMoma'': '''P'''apillary (thyroid, renal), '''S'''erous (ovary), '''M'''eningioma, '''M'''esothelioma.<ref>URL: [http://ome.umaryland.edu/AcademicD/practiceExams/path/path_findings.html http://ome.umaryland.edu/AcademicD/practiceExams/path/path_findings.html]. Accessed on: 15 January 2012.</ref> | ||
Isolated psammoma bodies in smears or aspirates are an unreliable predictor of papillary carcinoma. <ref>{{Cite journal | last1 = Ellison | first1 = E. | last2 = Lapuerta | first2 = P. | last3 = Martin | first3 = SE. | title = Psammoma bodies in fine-needle aspirates of the thyroid: predictive value for papillary carcinoma. | journal = Cancer | volume = 84 | issue = 3 | pages = 169-75 | month = Jun | year = 1998 | doi = | PMID = 9678732 }}</ref> | Isolated psammoma bodies in smears or aspirates are an unreliable predictor of papillary carcinoma. <ref>{{Cite journal | last1 = Ellison | first1 = E. | last2 = Lapuerta | first2 = P. | last3 = Martin | first3 = SE. | title = Psammoma bodies in fine-needle aspirates of the thyroid: predictive value for papillary carcinoma. | journal = Cancer | volume = 84 | issue = 3 | pages = 169-75 | month = Jun | year = 1998 | doi = | PMID = 9678732 }}</ref> | ||
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==See also== | ==See also== | ||
*[[Endometrium with psammoma bodies]]. | *[[Endometrium with psammoma bodies]]. | ||
*[[Calcifications]]. | |||
==References== | ==References== | ||