Lichen sclerosus: Difference between revisions
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| Gross = | | Gross = | ||
| Grossing = | | Grossing = | ||
| Site = [[vulva]], [[penis]] | | Site = [[vulva]], [[penis]], [[urethra]] | ||
| Assdx = [[differentiated vulvar intraepithelial neoplasia]], [[vulvar squamous cell carcinoma]] | | Assdx = [[differentiated vulvar intraepithelial neoplasia]], [[vulvar squamous cell carcinoma]] | ||
| Syndromes = | | Syndromes = | ||
| Clinicalhx = | | Clinicalhx = | ||
| Signs = | | Signs = | ||
| Symptoms = | | Symptoms = pruritus | ||
| Prevalence = | | Prevalence = | ||
| Bloodwork = | | Bloodwork = | ||
| Line 45: | Line 45: | ||
Clinical: | Clinical: | ||
* | *Pruritus -> leads to scratching. | ||
*Chronic condition. | *Chronic condition. | ||
*Usu. post-menopausal women. | *Usu. post-menopausal women. | ||
| Line 89: | Line 89: | ||
==Sign out== | ==Sign out== | ||
<pre> | |||
Foreskin, Circumcision: | |||
- Lichen sclerosus. | |||
- NEGATIVE for malignancy. | |||
</pre> | |||
===Block letters=== | |||
<pre> | <pre> | ||
VULVA, BIOPSY: | VULVA, BIOPSY: | ||
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===Micro=== | ===Micro=== | ||
==== | ====Inflammatory phase of lichen sclerosus==== | ||
The sections show skin with a lymphoplasmacytic predominant interface dermatitis with hyperkeratosis. Spongiosis is present. Scattered inflammatory cell are found with the basal aspect of the epidermis; however, they do not form clusters. No mitotic activity is appreciated. | The sections show skin with a lymphoplasmacytic predominant interface dermatitis with hyperkeratosis. Spongiosis is present. Scattered inflammatory cell are found with the basal aspect of the epidermis; however, they do not form clusters. No mitotic activity is appreciated. | ||