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Difference between revisions of "Cribriform adenocarcinoma of the minor salivary gland"
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Cribriform adenocarcinoma of the minor salivary gland (view source)
Revision as of 20:23, 25 February 2021
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| Caption = Cribriform adenocarcinoma of the minor salivary gland. [[H&E stain]]. | | Caption = Cribriform adenocarcinoma of the minor salivary gland. [[H&E stain]]. | ||
| Synonyms = cribriform | | Synonyms = cribriform adenocarcinoma of the tongue | ||
| Micro = cribriform and solid architecture, cytology similar to papillary thyroid carcinoma (irregular nuclear membranes, nuclear overlap), usually covered by an intact squamous epithelium | | Micro = cribriform and solid architecture, cytology similar to papillary thyroid carcinoma (irregular nuclear membranes, nuclear overlap), usually covered by an intact squamous epithelium | ||
| Subtypes = | | Subtypes = | ||
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'''Cribriform adenocarcinoma of the minor salivary gland''', abbreviated '''CAMSG''', is a rare [[malignancy]] of the [[salivary gland]], typically of the [[tongue]].<ref name=pmid21716087/> | '''Cribriform adenocarcinoma of the minor salivary gland''', abbreviated '''CAMSG''', is a rare [[malignancy]] of the [[salivary gland]], typically of the [[tongue]].<ref name=pmid21716087/> | ||
It is also known as '''cribriform | It is also known as '''cribriform adenocarcinoma of the tongue''', abbreviated '''CAT'''. | ||
The ''World Health Organization'' lumps this tumour with [[polymorphous adenocarcinoma]], a decision that is considered "controversial".<ref name=pmid29761209>{{cite journal |authors=Vander Poorten V, Triantafyllou A, Skálová A, Stenman G, Bishop JA, Hauben E, Hunt JL, Hellquist H, Feys S, De Bree R, Mäkitie AA, Quer M, Strojan P, Guntinas-Lichius O, Rinaldo A, Ferlito A |title=Polymorphous adenocarcinoma of the salivary glands: reappraisal and update |journal=Eur Arch Otorhinolaryngol |volume=275 |issue=7 |pages=1681–1695 |date=July 2018 |pmid=29761209 |doi=10.1007/s00405-018-4985-5 |url=}}</ref> | |||
==General== | ==General== | ||
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Features: | Features: | ||
*Typically covered by an intact squamous epithelium.<ref name=pmid21716087>{{Cite journal | last1 = Skalova | first1 = A. | last2 = Sima | first2 = R. | last3 = Kaspirkova-Nemcova | first3 = J. | last4 = Simpson | first4 = RH. | last5 = Elmberger | first5 = G. | last6 = Leivo | first6 = I. | last7 = Di Palma | first7 = S. | last8 = Jirasek | first8 = T. | last9 = Gnepp | first9 = DR. | title = Cribriform adenocarcinoma of minor salivary gland origin principally affecting the tongue: characterization of new entity. | journal = Am J Surg Pathol | volume = 35 | issue = 8 | pages = 1168-76 | month = Aug | year = 2011 | doi = 10.1097/PAS.0b013e31821e1f54 | PMID = 21716087 }}</ref> | *Typically covered by an intact squamous epithelium.<ref name=pmid21716087>{{Cite journal | last1 = Skalova | first1 = A. | last2 = Sima | first2 = R. | last3 = Kaspirkova-Nemcova | first3 = J. | last4 = Simpson | first4 = RH. | last5 = Elmberger | first5 = G. | last6 = Leivo | first6 = I. | last7 = Di Palma | first7 = S. | last8 = Jirasek | first8 = T. | last9 = Gnepp | first9 = DR. | title = Cribriform adenocarcinoma of minor salivary gland origin principally affecting the tongue: characterization of new entity. | journal = Am J Surg Pathol | volume = 35 | issue = 8 | pages = 1168-76 | month = Aug | year = 2011 | doi = 10.1097/PAS.0b013e31821e1f54 | PMID = 21716087 }}</ref> | ||
*Growth patterns - cribriform and solid. | *Growth patterns - [[cribriform]] and solid. | ||
*Cytology similar to [[papillary thyroid carcinoma]].<ref name=pmid21716087/> | *Cytology similar to [[papillary thyroid carcinoma]].<ref name=pmid21716087/> | ||
**Irregular nuclear membranes (raisin-like nuclei). | **Irregular nuclear membranes (raisin-like nuclei). | ||
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DDx: | DDx: | ||
*[[Polymorphous low grade adenocarcinoma | *[[Polymorphous adenocarcinoma]] (previously polymorphous low-grade adenocarcinoma) - morphology more varied. | ||
*[[Papillary thyroid carcinoma]]. | *[[Papillary thyroid carcinoma]]. | ||
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==Referencess== | ==Referencess== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Salivary gland]] | [[Category:Salivary gland]] | ||