Difference between revisions of "Myopericytoma"

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m (→‎Microscopic: +myofibroma)
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==Microscopic==
==Microscopic==
Features:
Features:<ref>{{cite journal |author=Edgecombe A, Peterson RA, Shamji FM, Commons S, Sekhon H, Gomes MM |title=Myopericytoma: a pleural-based spindle cell neoplasm off the beaten path |journal=Int. J. Surg. Pathol. |volume=19 |issue=2 |pages=247–51 |year=2011 |month=April |pmid=21474507 |doi=10.1177/1066896910381897 |url=}}</ref>
*Abundant, branching thin-walled blood vessels.
*Abundant, branching thin-walled blood vessels.
*Small bland epithelioid cells with moderate eosinophilic cytoplasm.
*Fasicular pattern - may be subtle.
**Unequally spaced cells (unlike glomus tumour).
*Cellular lesion:
**Small bland unequally spaced epithelioid/spindle cells.
**Moderate eosinophilic cytoplasm.


Notes:
Notes:
*Features overlap with [[myofibroma]].<ref name=pmid16394283>{{cite journal |author=Dray MS, McCarthy SW, Palmer AA, ''et al.'' |title=Myopericytoma: a unifying term for a spectrum of tumours that show overlapping features with myofibroma. A review of 14 cases |journal=J. Clin. Pathol. |volume=59 |issue=1 |pages=67–73 |year=2006 |month=January |pmid=16394283 |pmc=1860256 |doi=10.1136/jcp.2005.028704 |url=}}</ref>
*Features overlap with [[myofibroma]].<ref name=pmid16394283>{{cite journal |author=Dray MS, McCarthy SW, Palmer AA, ''et al.'' |title=Myopericytoma: a unifying term for a spectrum of tumours that show overlapping features with myofibroma. A review of 14 cases |journal=J. Clin. Pathol. |volume=59 |issue=1 |pages=67–73 |year=2006 |month=January |pmid=16394283 |pmc=1860256 |doi=10.1136/jcp.2005.028704 |url=}}</ref>
DDx:
*[[Solitary fibrous tumour]].


Images:
Images:
*[http://commons.wikimedia.org/wiki/File:Myopericytoma_-_b_-_high_mag.jpg Myopericytoma - high mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Myopericytoma_-_b_-_high_mag.jpg Myopericytoma - high mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Myopericytoma_-_intermed_mag.jpg Myopericytoma - intermed. mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Myopericytoma_-_intermed_mag.jpg Myopericytoma - intermed. mag. (WC)].
==IHC==
*Some muscle markers +ve.
*CD34 -ve.


==References==
==References==

Revision as of 07:42, 30 April 2011

Myopericytoma, also glomangiopericytoma, is a rare perivascular soft tissue tumour.

General

  • Usu. benign.
  • Typically in the distal extremities.[1]

Microscopic

Features:[2]

  • Abundant, branching thin-walled blood vessels.
  • Fasicular pattern - may be subtle.
  • Cellular lesion:
    • Small bland unequally spaced epithelioid/spindle cells.
    • Moderate eosinophilic cytoplasm.

Notes:

DDx:

Images:

IHC

  • Some muscle markers +ve.
  • CD34 -ve.

References

  1. Zidane A, Arsalane A, Harkat A, et al. (November 2010). "[Myopericytoma: an uncommon chest wall tumor]" (in French). Rev Mal Respir 27 (9): 1089–91. doi:10.1016/j.rmr.2010.09.017. PMID 21111282.
  2. Edgecombe A, Peterson RA, Shamji FM, Commons S, Sekhon H, Gomes MM (April 2011). "Myopericytoma: a pleural-based spindle cell neoplasm off the beaten path". Int. J. Surg. Pathol. 19 (2): 247–51. doi:10.1177/1066896910381897. PMID 21474507.
  3. Dray MS, McCarthy SW, Palmer AA, et al. (January 2006). "Myopericytoma: a unifying term for a spectrum of tumours that show overlapping features with myofibroma. A review of 14 cases". J. Clin. Pathol. 59 (1): 67–73. doi:10.1136/jcp.2005.028704. PMC 1860256. PMID 16394283. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860256/.