Anastomosing hemangioma of the kidney: Difference between revisions

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'''Anastomosing hemangioma''' a rare benign [[vascular tumour]] that is typically in the [[kidney]] and may mimic [[angiosarcoma]].<ref name=pmid19606014>{{Cite journal  | last1 = Montgomery | first1 = E. | last2 = Epstein | first2 = JI. | title = Anastomosing hemangioma of the genitourinary tract: a lesion mimicking angiosarcoma. | journal = Am J Surg Pathol | volume = 33 | issue = 9 | pages = 1364-9 | month = Sep | year = 2009 | doi = 10.1097/PAS.0b013e3181ad30a7 | PMID = 19606014 }}</ref>
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Anastomosing hemangioma of the kidney -- intermed mag.jpg
| Width      =
| Caption    = Anastomosing hemangioma of the kidney. [[H&E stain]].
| Synonyms  = renal anastomosing hemangioma
| Micro      = vascular tumour with architecture similar to splenic sinsoids, hobnailing, +/-[[hyaline globules]], +/-[[extramedullary hematopoiesis]]
| Subtypes  =
| LMDDx      = [[angiosarcoma]], other [[hemangioma]]s, other [[vascular tumours]], [[angiomyolipoma]]
| Stains    =
| IHC        = CD34 +ve, CD31 +ve, HHV-8
| EM        =
| Molecular  =
| IF        =
| Gross      = brown/mahogany lesion, classically centered on medulla of kidney
| Grossing  = [[total nephrectomy for tumour grossing]], [[partial nephrectomy grossing]]
| Staging    =
| Site      = [[kidney]]
| Assdx      = +/-[[end stage renal disease]]
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = very rare
| Bloodwork  =
| Rads      = may mimic [[renal cell carcinoma]]
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    = [[renal tumours]]
| Tx        = excision for definitive diagnosis?
}}
'''Anastomosing hemangioma of the kidney''' a rare benign [[vascular tumour]] of [[kidney]] that may mimic [[angiosarcoma]].<ref name=pmid19606014>{{Cite journal  | last1 = Montgomery | first1 = E. | last2 = Epstein | first2 = JI. | title = Anastomosing hemangioma of the genitourinary tract: a lesion mimicking angiosarcoma. | journal = Am J Surg Pathol | volume = 33 | issue = 9 | pages = 1364-9 | month = Sep | year = 2009 | doi = 10.1097/PAS.0b013e3181ad30a7 | PMID = 19606014 }}</ref>


==General==
==General==
*Rare - case reports.
*Rare - case reports.
**The bigger category ''vascular tumours of the kidney'' is rare; in the world literature (as of 2015), according to Omiyale, there are approximately 40 angiosarcoma and 220 hemangiomas.<ref name=pmid26244138>{{Cite journal  | last1 = Omiyale | first1 = AO. | title = Anastomosing hemangioma of the kidney: a literature review of a rare morphological variant of hemangioma. | journal = Ann Transl Med | volume = 3 | issue = 11 | pages = 151 | month = Jul | year = 2015 | doi = 10.3978/j.issn.2305-5839.2015.06.16 | PMID = 26244138 }}</ref>
*Typically seen in [[end stage renal disease]].<ref name=pmid27543862/>
*May mimic renal cell carcinoma clinically.<ref name=pmid28727378>{{Cite journal  | last1 = Silva | first1 = MA. | last2 = Fonseca | first2 = EKUN. | last3 = Yamauchi | first3 = FI. | last4 = Baroni | first4 = RH. | title = Anastomosing hemangioma simulating renal cell carcinoma. | journal = Int Braz J Urol | volume = 43 | issue = 5 | pages = 987-989 | month =  | year =  | doi = 10.1590/S1677-5538.IBJU.2016.0653 | PMID = 28727378 }}</ref>
==Gross==
Features:
*Mahogany/brown - centered on medulla of kidney.<ref name=pmid27543862/>


==Microscopic==
==Microscopic==
Features:
Features:
*Vascular tumour characterized by vessels that fuse/join (anastomose).
*Vascular tumour characterized by vessels that fuse/join (anastomose); described as ''splenic sinusoids-like''.<ref name=pmid27543862/>
**+/-Hobnail morphology
**+/-[[Hobnail morphology]].
**+/-Cytoplasmic hyaline globules.
*+/-[[Extramedullary hematopoiesis]].
**[[Nucleated red blood cell]]s.
**Megakaryocytes.


Note:
Note:
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DDx:
DDx:
*[[Angiosarcoma]] - nuclear atypia, more proliferative activity.
*[[Angiosarcoma]] - [[nuclear atypia]], more proliferative activity.
*[[Angiomyolipoma]].
 
===Images===
<gallery>
Image: Anastomosing hemangioma of the kidney -- low mag.jpg | AH - low mag. (WC)
Image: Anastomosing hemangioma of the kidney -- intermed mag.jpg | AH - intermed. mag. (WC)
Image: Anastomosing hemangioma of the kidney -- high mag.jpg | AH - high mag. (WC)
Image: Anastomosing hemangioma of the kidney -- very high mag.jpg | AH - very high mag. (WC)
 
Image: Anastomosing hemangioma of the kidney - alt -- extremely low mag.jpg | AH - extremely low mag. (WC)
Image: Anastomosing hemangioma of the kidney - alt -- very low mag.jpg | AH - very low mag. (WC)
Image: Anastomosing hemangioma of the kidney - alt -- low mag.jpg | AH - low mag. (WC)
Image: Anastomosing hemangioma of the kidney - alt -- intermed mag.jpg | AH - intermed. mag. (WC)
Image: Anastomosing hemangioma of the kidney - b -- intermed mag.jpg | AH - intermed. mag. (WC)
Image: Anastomosing hemangioma of the kidney - b -- high mag.jpg | AH - high mag. (WC)
</gallery>
 
==IHC==
Features:<ref name=pmid27543862>{{Cite journal  | last1 = Kuroda | first1 = N. | last2 = Ohe | first2 = C. | last3 = Deepika | first3 = S. | last4 = Yorita | first4 = K. | last5 = Mikami | first5 = S. | last6 = Furuya | first6 = M. | last7 = Nagashima | first7 = Y. | last8 = Hes | first8 = O. | last9 = Agaimy | first9 = A. | title = Review of renal anastomosing hemangioma with focus on clinical and pathological aspects. | journal = Pol J Pathol | volume = 67 | issue = 2 | pages = 97-101 | month = Jun | year = 2016 | doi =  | PMID = 27543862 }}</ref>
*CD31 +ve.
*CD34 +ve.
*HHV8 -ve.


==See also==
==See also==
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[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Soft tissue lesions]]
[[Category:Soft tissue lesions]]
[[Category:Kidney tumours]]
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