Difference between revisions of "Collagenous gastritis"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Collagenous gastritis H&E.jpg | |||
| Width = | |||
| Caption = | |||
| Micro = collagen band in superficial lamina propria | |||
| Subtypes = | |||
| LMDDx = [[amyloidosis of the stomach]], [[signet ring cell carcinoma]] | |||
| Stains = [[trichrome stain]] - demonstrate collagen | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[stomach]] | |||
| Assdx = [[celiac sprue]] (in adults), [[collagenous colitis]] (in adults) | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = +/-dyspepsia | |||
| Prevalence = extremely rare | |||
| Bloodwork = +/-[[anemia]] | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
'''Collagenous gastritis''' is an extremely rare pathology of the [[stomach]]. It is seen in children and adults. | |||
==General== | |||
*Very rare<ref name=pmid23363075>{{Cite journal | last1 = Jin | first1 = X. | last2 = Koike | first2 = T. | last3 = Chiba | first3 = T. | last4 = Kondo | first4 = Y. | last5 = Ara | first5 = N. | last6 = Uno | first6 = K. | last7 = Asano | first7 = N. | last8 = Iijima | first8 = K. | last9 = Imatani | first9 = A. | title = Collagenous gastritis. | journal = Dig Endosc | volume = 25 | issue = 5 | pages = 547-9 | month = Sep | year = 2013 | doi = 10.1111/j.1443-1661.2012.01391.x | PMID = 23363075 }}</ref> ~ 30 cases reported in world literature in 2009.<ref name=pmid19730387>{{Cite journal | last1 = Brain | first1 = O. | last2 = Rajaguru | first2 = C. | last3 = Warren | first3 = B. | last4 = Booth | first4 = J. | last5 = Travis | first5 = S. | title = Collagenous gastritis: reports and systematic review. | journal = Eur J Gastroenterol Hepatol | volume = 21 | issue = 12 | pages = 1419-24 | month = Dec | year = 2009 | doi = 10.1097/MEG.0b013e32832770fa | PMID = 19730387 }}</ref> | |||
===Clinical=== | |||
children:<ref name=pmid23538318>{{Cite journal | last1 = Hijaz | first1 = NM. | last2 = Septer | first2 = SS. | last3 = Degaetano | first3 = J. | last4 = Attard | first4 = TM. | title = Clinical outcome of pediatric collagenous gastritis: case series and review of literature. | journal = World J Gastroenterol | volume = 19 | issue = 9 | pages = 1478-84 | month = Mar | year = 2013 | doi = 10.3748/wjg.v19.i9.1478 | PMID = 23538318 }}</ref> | |||
*Dyspepsia or anemia. | |||
*Chronic. | |||
Adults:<ref name=pmid19730387/> | |||
*Loose stools. | |||
*Associated with ''[[celiac sprue]]'' or ''[[collagenous colitis]]''. | |||
==Gross== | |||
*Discoloured depression - focal.<ref name=pmid23363075/> (???) | |||
==Microscopic== | |||
Features: | |||
*Band of eosinophilic material (collagen) expands superficial lamina propria.<ref name=pmid23363075/> | |||
**Band of collagen must be as thick as RBC diameter. | |||
DDx: | |||
*[[Amyloidosis of the stomach]]. | |||
*[[Signet ring cell carcinoma]]. | |||
===Images=== | |||
<gallery> | |||
Image:Collagenous gastritis H&E.jpg|Collagenous gastritis - H&E staining, med. mag. (WC/MO) | |||
Image:Collagenous gastritis Masson trichrome.jpg|Collagenous gastritis - Masson trichrome, med. mag. (WC/MO) | |||
Image:Collagenous gastritis Sirius Red.jpg|Collagenous gastritis - Sirius Red, med. mag. (WC/MO) | |||
</gallery> | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602509/figure/F1/ Collagenous gastritis (nih.gov)].<ref name=pmid23363075/> | |||
==Stains== | |||
*[[Trichrome stain]] - highlights collagen. | |||
==See also== | |||
*[[Stomach]]. | |||
*[[Celiac disease]]. | |||
*[[Collagenous colitis]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Stomach]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
Latest revision as of 21:45, 29 September 2018
| Collagenous gastritis | |
|---|---|
| Diagnosis in short | |
 | |
|
| |
| LM | collagen band in superficial lamina propria |
| LM DDx | amyloidosis of the stomach, signet ring cell carcinoma |
| Stains | trichrome stain - demonstrate collagen |
| Site | stomach |
|
| |
| Associated Dx | celiac sprue (in adults), collagenous colitis (in adults) |
| Symptoms | +/-dyspepsia |
| Prevalence | extremely rare |
| Blood work | +/-anemia |
Collagenous gastritis is an extremely rare pathology of the stomach. It is seen in children and adults.
General
Clinical
children:[3]
- Dyspepsia or anemia.
- Chronic.
Adults:[2]
- Loose stools.
- Associated with celiac sprue or collagenous colitis.
Gross
- Discoloured depression - focal.[1] (???)
Microscopic
Features:
- Band of eosinophilic material (collagen) expands superficial lamina propria.[1]
- Band of collagen must be as thick as RBC diameter.
DDx:
Images
Collagenous gastritis - H&E staining, med. mag. (WC/MO)
Collagenous gastritis - Masson trichrome, med. mag. (WC/MO)
Collagenous gastritis - Sirius Red, med. mag. (WC/MO)
Stains
- Trichrome stain - highlights collagen.
See also
References
- ↑ 1.0 1.1 1.2 1.3 Jin, X.; Koike, T.; Chiba, T.; Kondo, Y.; Ara, N.; Uno, K.; Asano, N.; Iijima, K. et al. (Sep 2013). "Collagenous gastritis.". Dig Endosc 25 (5): 547-9. doi:10.1111/j.1443-1661.2012.01391.x. PMID 23363075.
- ↑ 2.0 2.1 Brain, O.; Rajaguru, C.; Warren, B.; Booth, J.; Travis, S. (Dec 2009). "Collagenous gastritis: reports and systematic review.". Eur J Gastroenterol Hepatol 21 (12): 1419-24. doi:10.1097/MEG.0b013e32832770fa. PMID 19730387.
- ↑ Hijaz, NM.; Septer, SS.; Degaetano, J.; Attard, TM. (Mar 2013). "Clinical outcome of pediatric collagenous gastritis: case series and review of literature.". World J Gastroenterol 19 (9): 1478-84. doi:10.3748/wjg.v19.i9.1478. PMID 23538318.