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Difference between revisions of "Intraepithelial lymphocytes"
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'''Intraepithelial lymphocytes''', abbreviated '''IELs''', are seen in a number of contexts. | [[Image:Lymphocytic_proctitis_--_intermed_mag.jpg|thumb|right|Lymphocytic proctitis. [[H&E stain]].]] | ||
'''Intraepithelial lymphocytes''', abbreviated '''IELs''', is the presence of lymphocytes between (benign) epithelial cells. IELs are seen in a number of contexts. | |||
The epithelial cells in the context of IEL are presumed to be benign. Lymphocytes infiltrating between malignant (epithelial) cells is dealt with in the ''[[tumour infiltrating lymphocytes]]'' article. | |||
==Small bowel== | ==Small bowel== | ||
*[[Celiac disease]. | *[[Celiac disease]] - classic cause. | ||
*[[Giardia]]. | *[[Giardia]]. | ||
*[[Helicobacter gastritis]]. | *[[Helicobacter gastritis]]. | ||
*[[Crohn's disease]].{{fact}} | |||
*Morbid [[obesity]].<ref name=pmid17516730>{{Cite journal | last1 = Harpaz | first1 = N. | last2 = Levi | first2 = GS. | last3 = Yurovitsky | first3 = A. | last4 = Kini | first4 = S. | title = Intraepithelial lymphocytosis in architecturally normal small intestinal mucosa: association with morbid obesity. | journal = Arch Pathol Lab Med | volume = 131 | issue = 3 | pages = 344; author reply 344 | month = Mar | year = 2007 | doi = 10.1043/1543-2165(2007)131[344b:IR]2.0.CO;2 | PMID = 17516730 }}</ref> | |||
==Large Bowel== | ==Large Bowel== | ||
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*[[Celiac disease]].<ref name=pmid9865829>{{Cite journal | last1 = Fine | first1 = KD. | last2 = Lee | first2 = EL. | last3 = Meyer | first3 = RL. | title = Colonic histopathology in untreated celiac sprue or refractory sprue: is it lymphocytic colitis or colonic lymphocytosis? | journal = Hum Pathol | volume = 29 | issue = 12 | pages = 1433-40 | month = Dec | year = 1998 | doi = | PMID = 9865829 }}</ref> | *[[Celiac disease]].<ref name=pmid9865829>{{Cite journal | last1 = Fine | first1 = KD. | last2 = Lee | first2 = EL. | last3 = Meyer | first3 = RL. | title = Colonic histopathology in untreated celiac sprue or refractory sprue: is it lymphocytic colitis or colonic lymphocytosis? | journal = Hum Pathol | volume = 29 | issue = 12 | pages = 1433-40 | month = Dec | year = 1998 | doi = | PMID = 9865829 }}</ref> | ||
*[[Crohn's disease]].<ref name=pmid10478667>{{Cite journal | last1 = Goldstein | first1 = NS. | last2 = Gyorfi | first2 = T. | title = Focal lymphocytic colitis and collagenous colitis: patterns of Crohn's colitis? | journal = Am J Surg Pathol | volume = 23 | issue = 9 | pages = 1075-81 | month = Sep | year = 1999 | doi = | PMID = 10478667 }}</ref> | *[[Crohn's disease]].<ref name=pmid10478667>{{Cite journal | last1 = Goldstein | first1 = NS. | last2 = Gyorfi | first2 = T. | title = Focal lymphocytic colitis and collagenous colitis: patterns of Crohn's colitis? | journal = Am J Surg Pathol | volume = 23 | issue = 9 | pages = 1075-81 | month = Sep | year = 1999 | doi = | PMID = 10478667 }}</ref> | ||
*Drug-induced colitis.{{fact}} | |||
==See also== | ==See also== | ||