30
edits
Difference between revisions of "Juvenile polyp"
Jump to navigation
Jump to search
m
→Images
(+cat.) |
m (→Images) |
||
| (4 intermediate revisions by one other user not shown) | |||
| Line 1: | Line 1: | ||
{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Gastric_juvenile_polyp_-_very_low_mag.jpg | |||
| Width = | |||
| Caption = Juvenile polyp (stomach). [[H&E stain]]. | |||
| Micro = eroded, smooth or lobulated surface, pedunculated, increased lamina propria (LP) +/- edema, | |||
cystically dilated gland, +/-inflammation | |||
| Subtypes = | |||
| LMDDx = [[inflammatory polyp]], [[hyperplastic polyp of the stomach]], [[Cronkhite-Canada syndrome]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[gastrointestinal tract polyps]] | |||
| Assdx = | |||
| Syndromes = [[Juvenile polyposis syndrome]] | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign itself; multiple = marker of increased risk of malignancy | |||
| Other = | |||
| ClinDDx = other [[GI polyps]] | |||
}} | |||
'''Juvenile polyp''', abbreviated '''JP''', is a type of [[hamartoma|hamartomatous]][[Gastrointestinal tract polyps|gastrointestinal polyp]]. | |||
In adults, it is known as a '''retention polyp'''. | |||
==General== | |||
*Uncommon. | |||
May be part of a syndrome: | |||
*[[Juvenile polyposis syndrome]] (JPS) - see JPS article for criteria. | |||
*[[Cronkhite-Canada syndrome]]. | |||
*[[Cowden syndrome]]. | |||
==Gross== | |||
*Mushroom-like shape. | |||
==Microscopic== | |||
Features:<ref name=Ref_PBoD859>{{Ref PBoD|859}}</ref><ref name=pmid12692201>{{Cite journal | last1 = Bronner | first1 = MP. | title = Gastrointestinal inherited polyposis syndromes. | journal = Mod Pathol | volume = 16 | issue = 4 | pages = 359-65 | month = Apr | year = 2003 | doi = 10.1097/01.MP.0000062992.54036.E4 | PMID = 12692201 | url = http://www.nature.com/modpathol/journal/v16/n4/full/3880773a.html }}</ref> | |||
*Eroded, smooth or lobulated surface. | |||
*Pedunculated. | |||
*Increased lamina propria (LP) +/- edema. | |||
*Cystically dilated gland. | |||
*Often inflammed. | |||
Mnemonic ''DIES'' = dilated glands, increased LP & inflammation of the LP, eroded/smooth surface, stalk. | |||
Notes: | |||
*May have nuclear changes like those seen in adenomatous polyps. | |||
DDx: | |||
*[[Inflammatory polyp]]. | |||
*[[Hyperplastic polyp of the stomach]] - less lamina propria, foveolar hyperplasia (long tortuous glands). | |||
*[[Cronkhite-Canada syndrome]] - have changes in the surrounding mucosa, clinical findings (nail atrophy, skin pigment, alopecia). | |||
===Images=== | |||
<gallery> | |||
Image:Gastric_juvenile_polyp_-_very_low_mag.jpg | Juvenile polyp of the stomach - very low mag. (WC/Nephron) | |||
Image:Gastric_juvenile_polyp_-_2_-_very_low_mag.jpg | Juvenile polyp of the stomach - very low mag. (WC/Nephron) | |||
</gallery> | |||
==IHC== | |||
*Usually none. | |||
Notes: | |||
*IHC can be used if it is suspected to have dysplasia (p53, Ki-67). | |||
**p53 mutations in dysplastic epithelium -- negative stain (normal). | |||
==Sign out== | |||
<pre> | |||
Polyp, Sigmoid Colon, Polypectomy: | |||
- Juvenile polyp/retention polyp. | |||
</pre> | |||
===Block letters=== | |||
<pre> | |||
RECTOSIGMOID POLYP, BIOPSY: | |||
- RETENTION POLYP. | |||
</pre> | |||
==See also== | |||
*[[Gastrointestinal tract polyps]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Gastrointestinal pathology]] | |||