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Difference between revisions of "Pseudoinvasion in colorectal adenomatous polyps"
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Pseudoinvasion in colorectal adenomatous polyps (view source)
Revision as of 06:27, 19 March 2018
, 06:27, 19 March 2018no edit summary
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'''Pseudoinvasion in colorectal adenomatous polyps''' is a mimic of invasive adenocarcinoma. | '''Pseudoinvasion in colorectal adenomatous polyps''', also '''epithelial misplacement''',<ref name=pmid25123305>{{Cite journal | last1 = Loughrey | first1 = MB. | last2 = Shepherd | first2 = NA. | title = The pathology of bowel cancer screening. | journal = Histopathology | volume = 66 | issue = 1 | pages = 66-77 | month = Jan | year = 2015 | doi = 10.1111/his.12530 | PMID = 25123305 }}</ref> is a mimic of (invasive) [[colorectal adenocarcinoma]]. | ||
'''Pseudoinvasion''' | '''Pseudoinvasion''' redirects to this article. | ||
==General== | ==General== | ||
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*[[Gastrointestinal_tract_polyps#Colorectal_adenocarcinoma|Colorectal adenocarcinoma]]. | *[[Gastrointestinal_tract_polyps#Colorectal_adenocarcinoma|Colorectal adenocarcinoma]]. | ||
**Adenoma-like adenocarcinoma.<ref name=pmid25913616>{{Cite journal | last1 = Gonzalez | first1 = RS. | last2 = Cates | first2 = JM. | last3 = Washington | first3 = MK. | last4 = Beauchamp | first4 = RD. | last5 = Coffey | first5 = RJ. | last6 = Shi | first6 = C. | title = Adenoma-like adenocarcinoma: a subtype of colorectal carcinoma with good prognosis, deceptive appearance on biopsy and frequent KRAS mutation. | journal = Histopathology | volume = 68 | issue = 2 | pages = 183-90 | month = Jan | year = 2016 | doi = 10.1111/his.12725 | PMID = 25913616 }}</ref> | **Adenoma-like adenocarcinoma.<ref name=pmid25913616>{{Cite journal | last1 = Gonzalez | first1 = RS. | last2 = Cates | first2 = JM. | last3 = Washington | first3 = MK. | last4 = Beauchamp | first4 = RD. | last5 = Coffey | first5 = RJ. | last6 = Shi | first6 = C. | title = Adenoma-like adenocarcinoma: a subtype of colorectal carcinoma with good prognosis, deceptive appearance on biopsy and frequent KRAS mutation. | journal = Histopathology | volume = 68 | issue = 2 | pages = 183-90 | month = Jan | year = 2016 | doi = 10.1111/his.12725 | PMID = 25913616 }}</ref> | ||
==IHC=== | |||
*MMP-1, p53, E-cadherin, collagen IV - may have some utility.<ref name=pmid11812942>{{Cite journal | last1 = Yantiss | first1 = RK. | last2 = Bosenberg | first2 = MW. | last3 = Antonioli | first3 = DA. | last4 = Odze | first4 = RD. | title = Utility of MMP-1, p53, E-cadherin, and collagen IV immunohistochemical stains in the differential diagnosis of adenomas with misplaced epithelium versus adenomas with invasive adenocarcinoma. | journal = Am J Surg Pathol | volume = 26 | issue = 2 | pages = 206-15 | month = Feb | year = 2002 | doi = | PMID = 11812942 }}</ref> | |||
**Probably not useful for difficult cases. | |||
==Sign out== | ==Sign out== | ||
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==See also== | ==See also== | ||
*[[Gastrointestinal tract polyps]]. | *[[Gastrointestinal tract polyps]]. | ||
*[[Intramucosal adenocarcinoma of the colon]]. | |||
==References== | ==References== | ||