Difference between revisions of "Intestinal spirochetosis"
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===Images=== | ===Images=== | ||
*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830567/figure/F3/ Spirochetes shown with a Warthin-Starry stain (nih.gov)].<ref name=pmid20200654>{{Cite journal | last1 = Tsinganou | first1 = E. | last2 = Gebbers | first2 = JO. | title = Human intestinal spirochetosis--a review. | journal = Ger Med Sci | volume = 8 | issue = | pages = Doc01 | month = Jan | year = 2010 | doi = 10.3205/000090 | PMID = 20200654 }}</ref> | *[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830567/figure/F3/ Spirochetes shown with a Warthin-Starry stain (nih.gov)].<ref name=pmid20200654>{{Cite journal | last1 = Tsinganou | first1 = E. | last2 = Gebbers | first2 = JO. | title = Human intestinal spirochetosis--a review. | journal = Ger Med Sci | volume = 8 | issue = | pages = Doc01 | month = Jan | year = 2010 | doi = 10.3205/000090 | PMID = 20200654 }}</ref> | ||
==Sign out== | |||
<pre> | |||
Rectum, Biopsy: | |||
- Colonic-type mucosa with spirochetes, otherwise within normal limits. | |||
Comment: | |||
The presence of spirochetes was confirmed with a Warthin-Starry stain. | |||
</pre> | |||
==See also== | ==See also== |
Revision as of 19:34, 23 October 2017
Intestinal spirochetosis | |
---|---|
Diagnosis in short | |
![]() Intestinal spirochetosis. H&E stain. | |
| |
LM | hyperchromatic fuzz on luminal aspect of epithelial cells - at brush border; spirochetes |
Stains | silver stains, e.g. Warthin-Starry stain |
Site | intestine - colon |
| |
Signs | watery diarrhea +/-blood per rectum |
Symptoms | abdominal pain |
Prevalence | uncommon |
Prognosis | benign |
Clin. DDx | other causes of diarrhea |
Treatment | antibiotics |
Intestinal spirochetosis, also known as intestinal spirochetes, in an uncommon intestinal infection.
It is usually in the colon; thus, also known as colonic spirochetes and colonic spirochetosis.
General
- Caused by spirochetes[1][2] - specifically Brachyspira piloicoli[3] (previously Serpulina pilosicoli[4]) and Brachyspira aalborgi.
- Very rare cause of diarrhea, associated with male homosexual behaviour.
Symptoms:[2]
- Watery diarrhea, abdominal pain, +/-blood per rectum.
Treatment:[5]
- Metronidazole.
Microscopic
Features:
- Hyperchromatic fuzz on luminal aspect of epithelial cells; at brush border.
DDx:
- Normal colon.
- Infectious colitis without a distinctive morphology.
Images
www:
Special stains
- Silver stains highlight 'em (e.g. Warthin-Starry stain).
Images
Sign out
Rectum, Biopsy: - Colonic-type mucosa with spirochetes, otherwise within normal limits. Comment: The presence of spirochetes was confirmed with a Warthin-Starry stain.
See also
References
- ↑ Amat Villegas I, Borobio Aguilar E, Beloqui Perez R, de Llano Varela P, Oquiñena Legaz S, Martínez-Peñuela Virseda JM (January 2004). "[Colonic spirochetes: an infrequent cause of adult diarrhea]" (in Spanish; Castilian). Gastroenterol Hepatol 27 (1): 21–3. PMID 14718105.
- ↑ 2.0 2.1 URL: http://www.jhasim.com/files/articlefiles/pdf/XASIM_Master_6_5_May_Vignette.pdf. Accessed on: 25 April 2011.
- ↑ Margawani, KR.; Robertson, ID.; Hampson, DJ. (Feb 2009). "Isolation of the anaerobic intestinal spirochaete Brachyspira pilosicoli from long-term residents and Indonesian visitors to Perth, Western Australia.". J Med Microbiol 58 (Pt 2): 248-52. doi:10.1099/jmm.0.004770-0. PMID 19141744. http://ukpmc.ac.uk/abstract/MED/19141744/abstract/MED/19141744?ukpmc_extredirect=http://dx.doi.org/10.1099/jmm.0.004770-0.
- ↑ URL: http://www.cdc.gov/ncidod/eid/vol12no05/05-1180.htm. Accessed on: 28 June 2011.
- ↑ Calderaro A, Bommezzadri S, Gorrini C, et al. (November 2007). "Infective colitis associated with human intestinal spirochetosis". J. Gastroenterol. Hepatol. 22 (11): 1772–9. doi:10.1111/j.1440-1746.2006.04606.x. PMID 17914949.
- ↑ Tsinganou, E.; Gebbers, JO. (Jan 2010). "Human intestinal spirochetosis--a review.". Ger Med Sci 8: Doc01. doi:10.3205/000090. PMID 20200654.