49,256
edits
Difference between revisions of "Fibrosing pleuritis"
Jump to navigation
Jump to search
→Microscopic
| (7 intermediate revisions by the same user not shown) | |||
| Line 24: | Line 24: | ||
DDx:<ref name=pmid15559051>{{Cite journal | last1 = Corson | first1 = JM. | title = Pathology of mesothelioma. | journal = Thorac Surg Clin | volume = 14 | issue = 4 | pages = 447-60 | month = Nov | year = 2004 | doi = 10.1016/j.thorsurg.2004.06.007 | PMID = 15559051 }}</ref> | DDx:<ref name=pmid15559051>{{Cite journal | last1 = Corson | first1 = JM. | title = Pathology of mesothelioma. | journal = Thorac Surg Clin | volume = 14 | issue = 4 | pages = 447-60 | month = Nov | year = 2004 | doi = 10.1016/j.thorsurg.2004.06.007 | PMID = 15559051 }}</ref> | ||
*[[Mesothelioma]], desmoplastic. | *[[Mesothelioma]], desmoplastic. | ||
*[[Pleural plaques]]. | |||
*[[Empyema]] with fibrosis.<ref name=pmid6284084>{{Cite journal | last1 = McCabe | first1 = TA. | last2 = Rakowski | first2 = TA. | last3 = Argy | first3 = WP. | last4 = Reilly | first4 = MJ. | title = Fibrosing uremic pleuritis complicated by thoracic empyema. | journal = Arch Intern Med | volume = 142 | issue = 7 | pages = 1369-70 | month = Jul | year = 1982 | doi = | PMID = 6284084 }}</ref> | |||
==IHC== | ==IHC== | ||
*p53 -ve/+ve. | *p53 -ve/+ve. | ||
**More common in mesothelioma.<ref name=pmid9704618>{{Cite journal | last1 = Mangano | first1 = WE. | last2 = Cagle | first2 = PT. | last3 = Churg | first3 = A. | last4 = Vollmer | first4 = RT. | last5 = Roggli | first5 = VL. | title = The diagnosis of desmoplastic malignant mesothelioma and its distinction from fibrous pleurisy: a histologic and immunohistochemical analysis of 31 cases including p53 immunostaining. | journal = Am J Clin Pathol | volume = 110 | issue = 2 | pages = 191-9 | month = Aug | year = 1998 | doi = | PMID = 9704618 }}</ref> | **More common in mesothelioma.<ref name=pmid9704618>{{Cite journal | last1 = Mangano | first1 = WE. | last2 = Cagle | first2 = PT. | last3 = Churg | first3 = A. | last4 = Vollmer | first4 = RT. | last5 = Roggli | first5 = VL. | title = The diagnosis of desmoplastic malignant mesothelioma and its distinction from fibrous pleurisy: a histologic and immunohistochemical analysis of 31 cases including p53 immunostaining. | journal = Am J Clin Pathol | volume = 110 | issue = 2 | pages = 191-9 | month = Aug | year = 1998 | doi = | PMID = 9704618 }}</ref> | ||
==Sign out== | |||
<pre> | |||
Pleura, Left Lung, Biopsy: | |||
- Fibrous pleuritis/pleural plaque (fibrous tissue with mild chronic inflammation | |||
and calcifications). | |||
- NEGATIVE for evidence of malignancy. | |||
</pre> | |||
===Micro=== | |||
The sections show dense fibrous tissue with bland appearing fibroblasts and mild chronic inflammation. Large calcifications are present. Lung parenchyma is not seen. | |||
Nodular areas are not apparent. Concerning hypercellular areas are not seen. Necrosis is not present. Nuclear atypia is not identified. Mitotic activity is not readily apparent. | |||
==See also== | ==See also== | ||