Difference between revisions of "E-cadherin"
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Revision as of 05:29, 23 January 2017
E-cadherin is a common immunostain.
Mutations in the epithelial cadherin gene (E-cadherin), also known as CDH1, are associated with hereditary diffuse gastric cancer syndrome).[1][2]
Negative
- Lobular breast carcinoma.
- Atypical lobular hyperplasia.
- Lobular carcinoma in situ.
- Gastric adenocarcinoma, diffuse type.
Images
Normal
Normal stain pattern:
- Complete membrane staining.
Comment:
- Partial loss is considered negative staining.