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Difference between revisions of "Pleomorphic undifferentiated sarcoma"
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Pleomorphic undifferentiated sarcoma (view source)
Revision as of 18:04, 2 January 2017
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| Micro = storiform pattern ([[AKA]] ''patternless pattern''), marked [[nuclear pleomorphism]], mitoses, necrosis (common), mix of spindle cells and epithelioid cells, deep to skin | | Micro = storiform pattern ([[AKA]] ''patternless pattern''), marked [[nuclear pleomorphism]], mitoses, necrosis (common), mix of spindle cells and epithelioid cells, deep to skin | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[atypical fibroxanthoma]] (superficial), [[dedifferentiated liposarcoma]], [[leiomyosarcoma]],[[metaplastic carcinoma]], [[malignant melanoma]], [[rhabdomyosarcoma]], [[synovial sarcoma]],[[ | | LMDDx = [[atypical fibroxanthoma]] (superficial), [[dedifferentiated liposarcoma]], [[leiomyosarcoma]],[[metaplastic carcinoma]], [[malignant melanoma]], [[rhabdomyosarcoma]], [[synovial sarcoma]],[[undifferentiated endometrial sarcoma]], others | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = | ||
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Image:Pleomorphic_undifferentiated_sarcoma_-_intermed_mag.jpg | PUS - intermed. mag. (WC/Nephron) | Image:Pleomorphic_undifferentiated_sarcoma_-_intermed_mag.jpg | PUS - intermed. mag. (WC/Nephron) | ||
</gallery> | </gallery> | ||
[[File:3 13646052598462 sl 1.png|Pleomorphic sarcoma]] | |||
[[File:3 13646052598462 sl 2.png|Pleomorphic sarcoma]] | |||
[[File:3 13646052598462 sl 3.png|Pleomorphic sarcoma]] | |||
[[File:3 13646052598462 sl 4.png|Pleomorphic sarcoma]]<br> | |||
Pleomorphic sarcoma in thigh of late middle aged man. A. Tumor haphazardly spreads and invades and surrounds degenerated skeletal muscle fibers. B. Bizarre, sometimes multinucleated cells are seen. C. In other areas, spindle cells predominate. D. Invasion of adipose tissue by tumor should not be interpreted as proof of dedifferentiated liposarcoma; lipoblasts should be seen. Vital is remembering this is a diagnosis of exclusion, with negative keratin, CD34, CD30, S100, and CD31 stains being suggested. | |||
===Subclassification=== | ===Subclassification=== | ||