Difference between revisions of "Pankeratin"
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'''Pankeratin''' (abbreviated '''panker''), also known as '''pancytokeratin''', refers to an [[immunostain]] that markers abroad array of keratins. | [[Image:Prostate carcinoma with inflammation - panker -- low mag.jpg|right|thumb|350px|Pankeratin immunostain showing benign prostatic glands (left of image) and [[prostatic carcinoma]] (right of image).]] | ||
'''Pankeratin''' (abbreviated '''panker'''), also known as '''pancytokeratin''', refers to an [[immunostain]] that markers abroad array of keratins. | |||
''Keratin'' may be used as a synonym for ''pankeratin''. A general discussion about different types of ''keratins'' is found in the ''[[keratins]]'' article. | |||
==Overview== | |||
Several pankeratins exists;<ref name=pmid10975928>{{Cite journal | last1 = Xu | first1 = X. | last2 = Roberts | first2 = SA. | last3 = Pasha | first3 = TL. | last4 = Zhang | first4 = PJ. | title = Undesirable cytokeratin immunoreactivity of native nonepithelial cells in sentinel lymph nodes from patients with breast carcinoma. | journal = Arch Pathol Lab Med | volume = 124 | issue = 9 | pages = 1310-3 | month = Sep | year = 2000 | doi = 10.1043/0003-9985(2000)124<1310:UCIONN>2.0.CO;2 | PMID = 10975928 }}</ref> thus, ''pankeratin'' as a descriptor is not very specific. | Several pankeratins exists;<ref name=pmid10975928>{{Cite journal | last1 = Xu | first1 = X. | last2 = Roberts | first2 = SA. | last3 = Pasha | first3 = TL. | last4 = Zhang | first4 = PJ. | title = Undesirable cytokeratin immunoreactivity of native nonepithelial cells in sentinel lymph nodes from patients with breast carcinoma. | journal = Arch Pathol Lab Med | volume = 124 | issue = 9 | pages = 1310-3 | month = Sep | year = 2000 | doi = 10.1043/0003-9985(2000)124<1310:UCIONN>2.0.CO;2 | PMID = 10975928 }}</ref> thus, ''pankeratin'' as a descriptor is not very specific. | ||
==Examples of specific pankeratins== | |||
*Pan CK clone 5D3.<ref name=pmid10975928/> | |||
*Pan CK clone LP34.<ref name=pmid10975928/> | |||
*[[AE1/AE3]].<ref name=pmid10975928/> | |||
==See also== | ==See also== | ||
*[[Immunohistochemistry]]. | *[[Immunohistochemistry]]. | ||
*[[EMA]]. | |||
*[[AE1/AE3]]. | |||
==References== | ==References== | ||
Latest revision as of 03:31, 2 August 2016
Pankeratin immunostain showing benign prostatic glands (left of image) and prostatic carcinoma (right of image).
Pankeratin (abbreviated panker), also known as pancytokeratin, refers to an immunostain that markers abroad array of keratins.
Keratin may be used as a synonym for pankeratin. A general discussion about different types of keratins is found in the keratins article.
Overview
Several pankeratins exists;[1] thus, pankeratin as a descriptor is not very specific.
Examples of specific pankeratins
See also
References
- ↑ 1.0 1.1 1.2 1.3 Xu, X.; Roberts, SA.; Pasha, TL.; Zhang, PJ. (Sep 2000). "Undesirable cytokeratin immunoreactivity of native nonepithelial cells in sentinel lymph nodes from patients with breast carcinoma.". Arch Pathol Lab Med 124 (9): 1310-3. doi:10.1043/0003-9985(2000)124<1310:UCIONN>2.0.CO;2. PMID 10975928.