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Difference between revisions of "Keratins"
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''Keratin'' when used in singular may refer to ''[[pankeratin]]''. | ''Keratin'' when used in singular may refer to ''[[pankeratin]]''. | ||
==Classification== | |||
Divided by molecular weight:<ref>[http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm]</ref> | |||
*Low molecular weight keratins (LMWK): [[CK7|7]], 8/18, [[CK19|19]], [[CK20|20]]. | |||
*High molecular weight keratins (HWMK): 4, 10, 13, 14, 17. | |||
==Uses== | |||
*CK8 ([[CAM5.2]])<ref name=pmid7508102>{{cite journal |author=Murata T, Nakashima Y, Takeuchi M, Sueishi K, Inomata H |title=The diagnostic use of low molecular weight keratin expression in sebaceous carcinoma |journal=Pathol. Res. Pract. |volume=189 |issue=8 |pages=888–93 |year=1993 |month=September |pmid=7508102 |doi= |url=}}</ref> - used to look for mets from breast cancer in axillary lymph nodes. | |||
*HWMK (e.g. K903<ref>URL: [http://www.aruplab.com/guides/ug/tests/2003978.jsp http://www.aruplab.com/guides/ug/tests/2003978.jsp]. Accessed on: 17 March 2011.</ref>) - [[squamous cell carcinoma]]. | |||
==See also== | ==See also== | ||
*[[Immunohistochemistry]]. | *[[Immunohistochemistry]]. | ||
*[[Pankeratin]]. | *[[Pankeratin]]. | ||
==References== | |||
{{Reflist|1}} | |||
[[Category:Immunohistochemistry]] | [[Category:Immunohistochemistry]] | ||