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[[Image:High grade squamous intraepithelial lesion - 2 - p16 -- high mag.jpg|thumb|right| | [[Image:High grade squamous intraepithelial lesion - 2 - p16 -- high mag.jpg|thumb|right|250px|HSIL showing the characteristic p16 staining.]] | ||
[[Image:Endocervical adenocarcinoma in situ - p16 --- high mag.jpg|thumb|right|AIS showing the characteristic p16 staining.]] | |||
'''p16''' is a commonly used [[immunostain]]. It can be considered a surrogate marker for [[HPV]] infection. | '''p16''' is a commonly used [[immunostain]]. It can be considered a surrogate marker for [[HPV]] infection. | ||
p16, like most other "p" stains, is a nuclear stain. | p16, like most other "p" stains, is a nuclear stain. |
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