Difference between revisions of "Keratinising squamous metaplasia of the urinary bladder"
Jump to navigation
Jump to search
| Line 2: | Line 2: | ||
==General== | ==General== | ||
*Non-keratinizing squamous metaplasia can be considered normal and is relatively common in trigone region of the bladder in women. | *Rare.<ref name=pmid18931537/> | ||
**Non-keratinizing squamous metaplasia can be considered normal and is relatively common in trigone region of the bladder in women.{{fact}} | |||
*Large age range (13-80 years).<ref name=pmid12429156/> | *Large age range (13-80 years).<ref name=pmid12429156/> | ||
*Predominantly males - almost 4:1 (27 males:7 females in one series<ref name=pmid12429156/>). | *Predominantly males - almost 4:1 (27 males:7 females in one series<ref name=pmid12429156/>). | ||
Revision as of 13:10, 28 April 2016
Keratinising squamous metaplasia of the urinary bladder is a rare benign change of the urinary bladder associated with an increased risk of malignancy;[1] however, it is not considered a pre-malignant condition.[2][3]
General
- Rare.[3]
- Non-keratinizing squamous metaplasia can be considered normal and is relatively common in trigone region of the bladder in women.[citation needed]
- Large age range (13-80 years).[1]
- Predominantly males - almost 4:1 (27 males:7 females in one series[1]).
Treatment:
- Follow-up is recommended.[3]
Microscopic
Features:
- Squamous epithelium with hyperkeratosis or parakeratosis.
DDx:
- Squamous dysplasia of the metaplastic epithelium.
- Squamous cell carcinoma of the urinary bladder.
- Metastatic squamous cell carcinoma, e.g. squamous cell carcinoma of the uterine cervix.
Sign out
Urinary Bladder Lesion, Biopsy: - Extensive squamous metaplasia with degenerative changes and acute and chronic inflammation. - NEGATIVE for dysplasia and NEGATIVE for malignancy. Comment: Follow-up is recommended.
See also
References
- ↑ 1.0 1.1 1.2 Khan, MS.; Thornhill, JA.; Gaffney, E.; Loftus, B.; Butler, MR. (Nov 2002). "Keratinising squamous metaplasia of the bladder: natural history and rationalization of management based on review of 54 years experience.". Eur Urol 42 (5): 469-74. PMID 12429156.
- ↑ Kvist, E.; Sjølin, KE.; Laursen, H.; Orntoft, TF.; Sturmer, MA. (Jul 1992). "Squamous cell metaplasia of the bladder urothelium. A retrospective study of 36 patients.". APMIS 100 (7): 650-4. PMID 1379440.
- ↑ 3.0 3.1 3.2 Ahmad, I.; Barnetson, RJ.; Krishna, NS. (2008). "Keratinizing squamous metaplasia of the bladder: a review.". Urol Int 81 (3): 247-51. doi:10.1159/000151398. PMID 18931537.