Thecoma: Difference between revisions
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'''Thecoma''' is an [[ovarian tumour]] | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Thecoma_high_mag.jpg | |||
| Width = | |||
| Caption = Thecoma. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = bland oval or spindled nuclei, abundant cytoplasm that is pale and vaculolated | |||
| Subtypes = | |||
| LMDDx = [[ovarian fibroma]], fibroma-thecoma | |||
| Stains = | |||
| IHC = alpha-inhibin +ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = solid yellow mass, usually well-circumscribed | |||
| Grossing = | |||
| Site = [[ovary]] - see ''[[ovarian tumours]]'' | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = other [[ovarian tumours]] | |||
| Tx = | |||
}} | |||
'''Thecoma''' is an [[ovarian tumour|ovarian]] [[Sex cord-stromal tumours|sex-cord stromal tumour]]. | |||
==General== | ==General== | ||
| Line 8: | Line 39: | ||
==Gross== | ==Gross== | ||
Features: | Features: | ||
*Solid yellow mass, | *Solid yellow mass, usually well-circumscribed.<ref name=Ref_AoGP398>{{Ref AoGP|398}}</ref> | ||
DDx: | DDx: | ||
| Line 15: | Line 46: | ||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid16810055/> | Features:<ref name=pmid16810055>{{Cite journal | last1 = Roth | first1 = LM. | title = Recent advances in the pathology and classification of ovarian sex cord-stromal tumors. | journal = Int J Gynecol Pathol | volume = 25 | issue = 3 | pages = 199-215 | month = Jul | year = 2006 | doi = 10.1097/01.pgp.0000192271.22289.e6 | PMID = 16810055 }}</ref> | ||
*Nuclei with oval to spindle morphology. | *Nuclei with oval to spindle morphology. | ||
*Abundant cytoplasm that is pale, vaculolated -- '''key feature'''. | *Abundant cytoplasm that is pale, vaculolated -- '''key feature'''. | ||
DDx: | |||
*[[Ovarian fibroma]]. | |||
*[[Leiomyoma]] - rare. | |||
*Other [[sex cord-stromal tumour]]s. | |||
===Images=== | ===Images=== | ||
| Line 27: | Line 63: | ||
==IHC== | ==IHC== | ||
*Alpha-inhibin +ve (90%+).<ref name=pmid16810055/> | *Alpha-inhibin +ve (90%+).<ref name=pmid16810055/> | ||
==See also== | |||
*[[Ovarian tumours]]. | |||
*[[Ovarian fibroma]]. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Ovarian tumours]] | [[Category:Ovarian tumours]] | ||