Squamous metaplasia of the uterine cervix: Difference between revisions
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Endocervical_epithelium_and_squamous_metaplasia_--_very_high_mag.jpg | |||
| Width = | |||
| Caption = Squamous metaplasia and endocervical epithelium. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = uniform cell spacing (no "crowding"), nuclei are uniform size and round, +/-[[nucleoli]], distinct cell borders +/- intercellular bridges visible (common), adjacent/closely associated with endocervical epithelium - classically sits on surface (immature metaplasia), mitoses - rare, usually no nuclear hyperchromasia | |||
| Subtypes = | |||
| LMDDx = [[HSIL]], [[reactive squamous epithelium of the uterine cervix]], [[squamous cell carcinoma of the uterine cervix]] | |||
| Stains = | |||
| IHC = p16 patchy +ve (''not'' diffuse), Ki-67 low & predominantly basal | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[uterine cervix]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = [[acetowhite lesion]] | |||
| Symptoms = none | |||
| Prevalence = common | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = [[squamous intraepithelial lesion of the uterine cervix]] | |||
| Tx = | |||
}} | |||
'''Squamous metaplasia of the uterine cervix''' is a common change of the [[uterine cervix]] that may resemble [[squamous intraepithelial lesion]]. | '''Squamous metaplasia of the uterine cervix''' is a common change of the [[uterine cervix]] that may resemble [[squamous intraepithelial lesion]]. | ||
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===Images=== | ===Images=== | ||
<gallery> | |||
Image: Endocervical epithelium and squamous metaplasia -- high mag.jpg | Endocx and SM - high mag. | |||
Image: Endocervical epithelium and squamous metaplasia -- very high mag.jpg | Endocx and SM - very high mag. | |||
</gallery> | |||
www: | |||
*[http://www.sciencephoto.com/media/294722/view Squamous metaplasia - cervix (sciencephoto.com)]. | *[http://www.sciencephoto.com/media/294722/view Squamous metaplasia - cervix (sciencephoto.com)]. | ||
*[http://commons.wikimedia.org/wiki/File:Bronchial_squamous_metaplasia.jpg Squamous metaplasia - bronchus (WC)]. | *[http://commons.wikimedia.org/wiki/File:Bronchial_squamous_metaplasia.jpg Squamous metaplasia - bronchus (WC)]. | ||
*[http://nih.techriver.net/patientImages%5C6676.jpg Squamous metaplasia - cytology (techriver.net | *[http://nih.techriver.net/patientImages%5C6676.jpg Squamous metaplasia - cytology (techriver.net)].<ref>URL: [http://nih.techriver.net/view.php?patientId=1 http://nih.techriver.net/view.php?patientId=1]. Accessed on: 17 September 2015.</ref> | ||
==IHC== | ==IHC== | ||