Difference between revisions of "Sarcomatoid carcinoma of the prostate"

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{{ Infobox diagnosis
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Name      = {{PAGENAME}}
| Image      =   
| Image      =  Sarcomatoid_prostate_carcinoma_-_alt_--_intermed_mag.jpg
| Width      =
| Width      =
| Caption    = Sarcomatoid carcinoma of the prostate. [[H&E stain]].
| Caption    = Sarcomatoid carcinoma of the prostate. [[H&E stain]].
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*#Spindle cells (sarcomatous component).
*#Spindle cells (sarcomatous component).
*#*May include components of: [[osteosarcoma]], [[chondrosarcoma]] and/or [[rhabdomyosarcoma]].
*#*May include components of: [[osteosarcoma]], [[chondrosarcoma]] and/or [[rhabdomyosarcoma]].
*#Glandular component (like conventional prostate carcinoma).
*#Epithelial (glandular) component (like conventional prostate carcinoma).


DDx:
*[[Sarcomatoid urothelial carcinoma]].
*[[Sarcoma]].
*[[Carcinocarcinoma]].
===Images===
Sarcomatoid carcinoma:
<gallery>
Image: Sarcomatoid prostate carcinoma -- low mag.jpg | SPC - low mag.
Image: Sarcomatoid prostate carcinoma -- intermed mag.jpg | SPC - intermed. mag.
Image: Sarcomatoid prostate carcinoma -- high mag.jpg | SPC - high mag.
Image: Sarcomatoid prostate carcinoma -- very high mag.jpg | SPC - very high mag.
Image: Sarcomatoid prostate carcinoma - alt -- intermed mag.jpg | SPC - intermed. mag.
Image: Sarcomatoid prostate carcinoma - alt -- high mag.jpg | SPC - high mag.
Image: Sarcomatoid prostate carcinoma - alt -- very high mag.jpg | SPC - very high mag.
</gallery>
Accompanying (conventional) prostatic carcinoma:
<gallery>
Image: Conventional prostate carcinoma -- intermed mag.jpg | SCP - intermed. mag.
Image: Conventional prostate carcinoma -- high mag.jpg | SCP - intermed. mag.
</gallery>
==IHC==
==IHC==
Features - typical:<ref name=Ref_GUP80>{{Ref GUP|77 & 80}}</ref>
Features - typical:<ref name=Ref_GUP80>{{Ref GUP|77 & 80}}</ref>

Revision as of 03:52, 17 July 2015

Sarcomatoid carcinoma of the prostate
Diagnosis in short

Sarcomatoid carcinoma of the prostate. H&E stain.
Subtypes (subtype of prostate carcinoma)
LM DDx sarcoma, sarcomatoid urothelial carcinoma
IHC PSA +ve, keratin +ve
Gross see prostate carcinoma
Grossing notes see prostate carcinoma
Site prostate gland - see prostate carcinoma
Syndromes see prostate carcinoma
Clinical history typically have history of conventional prostate carcinoma
Prevalence uncommon
Prognosis poor
Clin. DDx see prostate carcinoma
Treatment see prostate carcinoma

Sarcomatoid prostate carcinoma is a rare subtype of prostatic carcinoma.

General

  • Rare.[1]
  • Poor prognosis - estimated 20% mortality at one year.[1]

Microscopic

Features:[2]

DDx:

Images

Sarcomatoid carcinoma:

  • SPC - low mag.

  • SPC - intermed. mag.

  • SPC - high mag.

  • SPC - very high mag.

  • SPC - intermed. mag.

  • SPC - high mag.

  • SPC - very high mag.

Accompanying (conventional) prostatic carcinoma:

  • SCP - intermed. mag.

  • SCP - intermed. mag.

IHC

Features - typical:[2]

  • PSA +ve.
  • Keratin +ve.

See also

References

  1. ↑ 1.0 1.1 Hansel, DE.; Epstein, JI. (Oct 2006). "Sarcomatoid carcinoma of the prostate: a study of 42 cases.". Am J Surg Pathol 30 (10): 1316-21. doi:10.1097/01.pas.0000209838.92842.bf. PMID 17001164.
  2. ↑ 2.0 2.1 Zhou, Ming; Magi-Galluzzi, Cristina (2006). Genitourinary Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 77 & 80. ISBN 978-0443066771.
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