Difference between revisions of "Kidney metastasis"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Metastatic adenocarcinoma involving the kidney -- very low mag.jpg | |||
| Width = | |||
| Caption = Metastatic adenocarcinoma involving the kidney. [[H&E stain]]. | |||
| Synonyms = renal metastasis, metastatic disease involving the kidney | |||
| Micro = malignant neoplasm - morphology dependent on site of origin, often glandular | |||
| Subtypes = | |||
| LMDDx = [[urothelial carcinoma]], primary adenocarcinoma of the renal pelvis, [[unclassified renal cell carcinoma]] | |||
| Stains = | |||
| IHC = PAX8 -ve (usually), vimentin -ve (usually) | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = mass lesion - classically in cortex close to the glomerular vascular plexus | |||
| Grossing = | |||
| Site = [[kidney]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = +/-history malignancy | |||
| Signs = | |||
| Symptoms = +/-hematuria | |||
| Prevalence = rare | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = poor | |||
| Other = | |||
| ClinDDx = renal primary | |||
| Tx = | |||
}} | |||
'''Kidney metastasis''', also '''renal metastasis''', is a [[kidney tumour]] that arose elsewhere and spread to the [[kidney]]. | '''Kidney metastasis''', also '''renal metastasis''', is a [[kidney tumour]] that arose elsewhere and spread to the [[kidney]]. | ||
| Line 17: | Line 48: | ||
Note: | Note: | ||
*[[Urothelial carcinoma]] may be confused with [[squamous cell carcinoma of the lung]]. | *[[Urothelial carcinoma]] may be confused with [[squamous cell carcinoma of the lung]]. | ||
DDx: | |||
*[[Unclassified renal cell carcinoma]]. | |||
*Primary adenocarcinoma of the renal pelvis<ref name=pmid8239939>{{Cite journal | last1 = Spires | first1 = SE. | last2 = Banks | first2 = ER. | last3 = Cibull | first3 = ML. | last4 = Munch | first4 = L. | last5 = Delworth | first5 = M. | last6 = Alexander | first6 = NJ. | title = Adenocarcinoma of renal pelvis. | journal = Arch Pathol Lab Med | volume = 117 | issue = 11 | pages = 1156-60 | month = Nov | year = 1993 | doi = | PMID = 8239939 }}</ref> - if the tumour is [[adenocarcinoma]]. | |||
===Images=== | ===Images=== | ||
====Case==== | |||
<gallery> | |||
Image: Metastatic adenocarcinoma involving the kidney -- very low mag.jpg | Kidney metastasis - very low mag. | |||
Image: Metastatic adenocarcinoma involving the kidney -- low mag.jpg | Kidney metastasis - low mag. | |||
Image: Metastatic adenocarcinoma involving the kidney -- intermed mag.jpg | Kidney metastasis - intermed. mag. | |||
Image: Metastatic adenocarcinoma involving the kidney -- high mag.jpg | Kidney metastasis - high mag. | |||
Image: Metastatic adenocarcinoma involving the kidney - alt -- high mag.jpg | Kidney metastasis - high mag. | |||
Image: Kidney with chronic inflammation and fibrosis -- low mag.jpg | Inflamed kidney - low mag. | |||
Image: Kidney with chronic inflammation and fibrosis -- intermed mag.jpg | Inflamed kidney - intermed. mag. | |||
</gallery> | |||
====www==== | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566941/figure/F2/ Kidney metastasis (nih.gov)].<ref name=pmid23320514/> | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566941/figure/F2/ Kidney metastasis (nih.gov)].<ref name=pmid23320514/> | ||
Latest revision as of 01:42, 11 July 2015
| Kidney metastasis | |
|---|---|
| Diagnosis in short | |
 Metastatic adenocarcinoma involving the kidney. H&E stain. | |
|
| |
| Synonyms | renal metastasis, metastatic disease involving the kidney |
|
| |
| LM | malignant neoplasm - morphology dependent on site of origin, often glandular |
| LM DDx | urothelial carcinoma, primary adenocarcinoma of the renal pelvis, unclassified renal cell carcinoma |
| IHC | PAX8 -ve (usually), vimentin -ve (usually) |
| Gross | mass lesion - classically in cortex close to the glomerular vascular plexus |
| Site | kidney |
|
| |
| Clinical history | +/-history malignancy |
| Symptoms | +/-hematuria |
| Prevalence | rare |
| Prognosis | poor |
| Clin. DDx | renal primary |
Kidney metastasis, also renal metastasis, is a kidney tumour that arose elsewhere and spread to the kidney.
General
- Rare.
- History should be compelling.
Clinical:
- +/-Hematuria seen in 12-31% of cases.[1]
Gross
- Typically in cortex close to the glomerular vascular plexus.[2]
Microscopic
Features:
- Malignant neoplasm - morphology dependent on site of origin and type.
Note:
- Urothelial carcinoma may be confused with squamous cell carcinoma of the lung.
DDx:
- Unclassified renal cell carcinoma.
- Primary adenocarcinoma of the renal pelvis[3] - if the tumour is adenocarcinoma.
Images
Case
Kidney metastasis - very low mag.
Kidney metastasis - low mag.
Kidney metastasis - intermed. mag.
Kidney metastasis - high mag.
Kidney metastasis - high mag.
Inflamed kidney - low mag.
Inflamed kidney - intermed. mag.
www
See also
References
- ↑ Bailey, JE.; Roubidoux, MA.; Dunnick, NR.. "Secondary renal neoplasms.". Abdom Imaging 23 (3): 266-74. PMID 9569294.
- ↑ 2.0 2.1 Cai, J.; Liang, G.; Cai, Z.; Yang, T.; Li, S.; Yang, J. (2013). "Isolated renal metastasis from squamous cell lung cancer.". Multidiscip Respir Med 8 (1): 2. doi:10.1186/2049-6958-8-2. PMID 23320514.
- ↑ Spires, SE.; Banks, ER.; Cibull, ML.; Munch, L.; Delworth, M.; Alexander, NJ. (Nov 1993). "Adenocarcinoma of renal pelvis.". Arch Pathol Lab Med 117 (11): 1156-60. PMID 8239939.