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Difference between revisions of "Glioma"
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typo fix, image added and see also
Jensflorian (talk | contribs) (Source: Partly fron en.wikipedia.org and modified accordingly + frequency update) |
Jensflorian (talk | contribs) (typo fix, image added and see also) |
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[[Image:Glioblastoma_macro.jpg|thumb|right| A [[glioblastoma]], the most common glioma. (WC/sbrandner)]] | |||
''Gliomas'' are the most compon primary tumor in the [[brain]] and [[spinal cord]]. They originate from [[glia]]l cells and their precursors. | ''Gliomas'' are the most compon primary tumor in the [[brain]] and [[spinal cord]]. They originate from [[glia]]l cells and their precursors. | ||
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Some authors consider [[choroid plexus]] as a specific type of glia, but [[choroid plexus tumors]] are usually not covered under the umberella term '''glioma'''. | Some authors consider [[choroid plexus]] as a specific type of glia, but [[choroid plexus tumors]] are usually not covered under the umberella term '''glioma'''. | ||
===By grade=== | ===By WHO grade=== | ||
Gliomas are further categorized according to their grade, which is determined by [[pathology|pathologic]] evaluation of the tumor. | Gliomas are further categorized according to their grade, which is determined by [[pathology|pathologic]] evaluation of the tumor. | ||
*Low-grade gliomas [WHO grade II] are well-differentiated (not anaplastic); these tend to exhibit [[benign]] tendencies and portend a better prognosis for the patient. However, they have a uniform rate of recurrence and increase in grade over time so should be classified as malignant. | *Low-grade gliomas [WHO grade II] are well-differentiated (not anaplastic); these tend to exhibit [[cancer|benign]] tendencies and portend a better prognosis for the patient. However, they have a uniform rate of recurrence and increase in grade over time so should be classified as malignant. | ||
*High-grade [WHO grade III–IV] gliomas are undifferentiated or anaplastic; these are [[cancer|malignant]] and carry a worse prognosis. | *High-grade [WHO grade III–IV] gliomas are undifferentiated or anaplastic; these are [[cancer|malignant]] and carry a worse prognosis. | ||
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*The pontine is located in the pons of the brainstem. The brainstem has three parts (pons, midbrain, and medulla); the pons controls critical functions such as breathing, making surgery on these extremely dangerous. | *The pontine is located in the pons of the brainstem. The brainstem has three parts (pons, midbrain, and medulla); the pons controls critical functions such as breathing, making surgery on these extremely dangerous. | ||
== | ==Frequency== | ||
The relative frequency differs significantly between adults and children.<ref>{{Cite journal | last1 = Ostrom | first1 = QT. | last2 = Gittleman | first2 = H. | last3 = Liao | first3 = P. | last4 = Rouse | first4 = C. | last5 = Chen | first5 = Y. | last6 = Dowling | first6 = J. | last7 = Wolinsky | first7 = Y. | last8 = Kruchko | first8 = C. | last9 = Barnholtz-Sloan | first9 = J. | title = CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. | journal = Neuro Oncol | volume = 16 Suppl 4 | issue = | pages = iv1-63 | month = Oct | year = 2014 | doi = 10.1093/neuonc/nou223 | PMID = 25304271 }}</ref> | The relative frequency differs significantly between adults and children.<ref>{{Cite journal | last1 = Ostrom | first1 = QT. | last2 = Gittleman | first2 = H. | last3 = Liao | first3 = P. | last4 = Rouse | first4 = C. | last5 = Chen | first5 = Y. | last6 = Dowling | first6 = J. | last7 = Wolinsky | first7 = Y. | last8 = Kruchko | first8 = C. | last9 = Barnholtz-Sloan | first9 = J. | title = CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. | journal = Neuro Oncol | volume = 16 Suppl 4 | issue = | pages = iv1-63 | month = Oct | year = 2014 | doi = 10.1093/neuonc/nou223 | PMID = 25304271 }}</ref> | ||
*Adults: | *Adults: | ||
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** not further specified 4.2% | ** not further specified 4.2% | ||
==See also== | |||
[[Neuropathology tumours]] | |||
{{references}} | {{references}} | ||
[[Category:Neuropathology]] | [[Category:Neuropathology]] | ||