Intracystic papillary carcinoma of the breast: Difference between revisions
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = Breast PapillaryCarcinomaEncysted PA.JPG | | Image = Breast PapillaryCarcinomaEncysted PA.JPG | ||
| Width = | | Width = | ||
| Caption = Intracystic Papillary Breast Carcinoma. [[H&E stain]]. | | Caption = Intracystic Papillary Breast Carcinoma. [[H&E stain]]. | ||
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***ER staining will be heterologous in a benign lesion. | ***ER staining will be heterologous in a benign lesion. | ||
***Myoepithelial markers (calponin/p63/SMA +ve)s hould be positive in a benign lesion. | ***Myoepithelial markers (calponin/p63/SMA +ve)s hould be positive in a benign lesion. | ||
*[[Papillary ductal carcinoma in situ]] | *[[Papillary ductal carcinoma in situ]]. | ||
**Papillary DCIS shows myoepithelial cells (calponin/p63/SMA +ve) at the periphery of the involved spaces | **Papillary DCIS shows myoepithelial cells (calponin/p63/SMA +ve) at the periphery of the involved spaces | ||
**But papillary DCIS should be negative for myoepithelial cells within the focus of DCIS | **But papillary DCIS should be negative for myoepithelial cells within the focus of DCIS | ||
**Papillary intracystic carcinoma does not show myoepithelial cells at the periphery of the involved spaces | **Papillary intracystic carcinoma does not show myoepithelial cells at the periphery of the involved spaces | ||
*Invasive papillary carcinoma of the breast | *[[Invasive papillary carcinoma of the breast]]. | ||
**Similar architecture but no cystic space, frankly invasive. | **Similar architecture but no cystic space, frankly invasive. | ||
**Very rare. | **Very rare. | ||