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#Columnar cell change. | #Columnar cell change. | ||
#*Columnar cells with blebs ("snouts") - often have calcifications (purple). | #*Columnar cells with blebs ("snouts") - often have calcifications (purple). | ||
#Duct ectasia | |||
Duct ectasia | |||
#*Dilation of large ducts secondary to luminal obstruction by inspissated secretions | |||
#*Presentation | |||
#**~age 40-50, possibly with cheesy nipple discharge | |||
#*Pathology | |||
#**Duct lumen dilated and containing foamy macrophages | |||
#**Necrosis/shedding of epithelium | |||
#**If duct rupture: chronic and granulomatous inflammation of periductal region | |||
#**Fibrotic thickening of duct wall | |||
<gallery> | |||
Image:Breast DuctEctasia LP PA.JPG|Breast - Duct Ectasia - low power (SKB) | |||
Image:Breast DuctEctasia MP2 PA.JPG|Breast - Duct Ectasia - low power (SKB) | |||
Image:Breast DuctEctasia MP PA.JPG|Breast - Duct Ectasia - medium power (SKB) | |||
</gallery> | |||
#[[Fibroadenoma]]. | #[[Fibroadenoma]]. | ||
#*Abundant myxoid (light/blanched) stroma - very common. | #*Abundant myxoid (light/blanched) stroma - very common. |
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