49,030
edits
Difference between revisions of "Pulmonary infarct"
Jump to navigation
Jump to search
touch
(redirect) |
(touch) |
||
| (7 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Pulmonary_infarct_intermed_mag.jpg | |||
| Width = | |||
| Caption = Pulmonary infarct. [[H&E stain]]. | |||
| Synonyms = lung infarct | |||
| Micro = [[necrosis]] of alveolar walls - loss of nuclei, alveolar hemorrhage, +/-evidence of underlying cause | |||
| Subtypes = | |||
| LMDDx = see ''Associated Dx'' | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = lung periphery, classically described as wedge-shaped | |||
| Grossing = | |||
| Site = [[lung]] | |||
| Assdx = underlying causes: [[sickle cell disease]], [[pulmonary embolism]], [[vasculitides]], malignancy (e.g. [[lymphoma]]), drug toxicity, others | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = reverse halo sign | |||
| Endoscopy = | |||
| Prognosis = dependent on underlying cause | |||
| Other = | |||
| ClinDDx = | |||
| Tx = dependent on underlying cause | |||
}} | |||
'''Pulmonary infarct''' is the death of [[lung]] tissue due to oxygen deprivation. | |||
It is also known as a '''lung infarct''', '''lung infarction''', and '''pulmonary infarction'''. | |||
==General== | |||
*Uncommon because of the dual blood supply (systemic via the bronchial arteries, pulmonary via the pulmonary arteries). | |||
Common causes:<ref>URL: [http://emedicine.medscape.com/article/908045-overview http://emedicine.medscape.com/article/908045-overview]. Accessed on: 12 April 2012.</ref> | |||
*[[Pulmonary embolism]].<ref name=pmid23395814>{{Cite journal | last1 = Casullo | first1 = J. | last2 = Semionov | first2 = A. | title = Reversed halo sign in acute pulmonary embolism and infarction. | journal = Acta Radiol | volume = | issue = | pages = | month = Feb | year = 2013 | doi = 10.1177/0284185113475797 | PMID = 23395814 }}</ref> | |||
*[[Sickle cell disease]]. | |||
Less common causes: | |||
*Lymphoma, esp. [[acute promyelocytic leukemia]]. | |||
*Drugs, e.g. chemotherapy. | |||
*[[Vasculitis]]. | |||
*Others. | |||
==Gross== | |||
*Lung periphery, classically described as wedge-shaped. | |||
Note: | |||
*In a histologic section, the classic wedge-shaped infarct is triangular: | |||
**Base of triangle on the pleural aspect. | |||
**Point furthest from the pleura close to the compromised artery that lead to infarction. | |||
Radiology: | |||
*Reverse halo sign.<ref name=pmid23395814/> | |||
Images: | |||
*[http://www.sciencephoto.com/media/258474/enlarge Pulmonary infarct (sciencephoto.com)]. | |||
*[http://www.flickr.com/photos/pulmonary_pathology/3732297830/ Pulmonary infarct (flickr.com)] | |||
==Microscopic== | |||
Features: | |||
*[[Necrosis]] of alveolar walls - loss of nuclei. | |||
*Alveolar hemorrhage. | |||
===Image=== | |||
<gallery> | |||
Image:Pulmonary_infarct_intermed_mag.jpg | Pulmonary infarct - low mag. (WC) | |||
</gallery> | |||
==See also== | |||
*[[Pulmonary pathology]]. | |||
*[[Infarct]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Pulmonary pathology]] | |||