Difference between revisions of "Uterine tumour resembling an ovarian sex cord stromal tumour"
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==General== | ==General== | ||
*Super rare. | *Super rare. | ||
*Typically postmenopausal - mean age ~ 52 years.<ref name=pmid25150955/> | |||
*Usually presentation is [[abnormal uterine bleeding]].<ref name=pmid25150955>{{Cite journal | last1 = Blake | first1 = EA. | last2 = Sheridan | first2 = TB. | last3 = Wang | first3 = KL. | last4 = Takiuchi | first4 = T. | last5 = Kodama | first5 = M. | last6 = Sawada | first6 = K. | last7 = Matsuo | first7 = K. | title = Clinical characteristics and outcomes of uterine tumors resembling ovarian sex-cord tumors (UTROSCT): a systematic review of literature. | journal = Eur J Obstet Gynecol Reprod Biol | volume = 181 | issue = | pages = 163-70 | month = Oct | year = 2014 | doi = 10.1016/j.ejogrb.2014.07.050 | PMID = 25150955 }}</ref> | |||
*Prognosis good if tumour predominantly sex cord-like, i.e. ''Type 2''.<ref name=pmid25150955/> | |||
==Microscopic== | ==Microscopic== | ||
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Notes: | Notes: | ||
*May be subdivided into:<name=pmid25257516/> | *May be subdivided into:<name=pmid25257516/> | ||
**Type 1 <50% sex cord-component. | **Type 1 <50% sex cord-component (may be referred to as ''endometrial stromal tumour with sex cord-like elements''<ref name=pmid25150955/>). | ||
**Type 2 >50% sex cord-component. | **Type 2 >50% sex cord-component. | ||
DDx: | |||
*[[Endometrial stromal sarcoma]]. | |||
===Images=== | ===Images=== | ||
Revision as of 17:48, 23 February 2015
Uterine tumour resembling an ovarian sex cord stromal tumour, abbreviated UTROSCT, is a very rare uterine tumour.
General
- Super rare.
- Typically postmenopausal - mean age ~ 52 years.[1]
- Usually presentation is abnormal uterine bleeding.[1]
- Prognosis good if tumour predominantly sex cord-like, i.e. Type 2.[1]
Microscopic
Features:
- Look like sex cord tumour:[2]
- May have: anastomosing cords, trabeculae, small nests and/or tubules.
Notes:
- May be subdivided into:<name=pmid25257516/>
- Type 1 <50% sex cord-component (may be referred to as endometrial stromal tumour with sex cord-like elements[1]).
- Type 2 >50% sex cord-component.
DDx:
Images
IHC
Features:[5]
- Calretinin +ve (sex cord-like component).
- CD10 +ve (stroma).
- PR +ve.
- Inhibin +ve/-ve.
See also
References
- ↑ 1.0 1.1 1.2 1.3 Blake, EA.; Sheridan, TB.; Wang, KL.; Takiuchi, T.; Kodama, M.; Sawada, K.; Matsuo, K. (Oct 2014). "Clinical characteristics and outcomes of uterine tumors resembling ovarian sex-cord tumors (UTROSCT): a systematic review of literature.". Eur J Obstet Gynecol Reprod Biol 181: 163-70. doi:10.1016/j.ejogrb.2014.07.050. PMID 25150955.
- ↑ URL: http://www.nature.com/modpathol/journal/v19/n1/full/3800475a.html. Accessed on: 5 August 2010.
- ↑ Baker, P.; Oliva, E. (Mar 2007). "Endometrial stromal tumours of the uterus: a practical approach using conventional morphology and ancillary techniques.". J Clin Pathol 60 (3): 235-43. doi:10.1136/jcp.2005.031203. PMID 17347285.
- ↑ Hashmi, AA.; Faridi, N.; Edhi, MM.; Khan, M. (2014). "Uterine tumor resembling ovarian sex cord tumor (UTROSCT), case report with literature review.". Int Arch Med 7 (1): 47. doi:10.1186/1755-7682-7-47. PMID 25395990.
- ↑ Bakula-Zalewska, E.; Danska-Bidzinska, A.; Kowalewska, M.; Piascik, A.; Nasierowska-Guttmejer, A.; Bidzinski, M. (Dec 2014). "Uterine tumors resembling ovarian sex cord tumors, a clinicopathologic study of six cases.". Ann Diagn Pathol 18 (6): 329-32. doi:10.1016/j.anndiagpath.2014.08.009. PMID 25257516.