Difference between revisions of "Prostatic stromal tumour of uncertain malignant potential"

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DDx:
DDx:
*Prostatic stromal sarcoma.<ref name=pmid22388992>{{Cite journal  | last1 = De Berardinis | first1 = E. | last2 = Busetto | first2 = GM. | last3 = Antonini | first3 = G. | last4 = Giovannone | first4 = R. | last5 = Di Placido | first5 = M. | last6 = Magliocca | first6 = FM. | last7 = Di Silverio | first7 = A. | last8 = Gentile | first8 = V. | title = Incidental prostatic stromal tumor of uncertain malignant potential (STUMP): histopathological and immunohistochemical findings. | journal = Urologia | volume = 79 | issue = 1 | pages = 65-8 | month =  | year = 2012 | doi = 10.5301/RU.2012.9099 | PMID = 22388992 }}</ref>
*[[Prostatic stromal sarcoma]].<ref name=pmid22388992>{{Cite journal  | last1 = De Berardinis | first1 = E. | last2 = Busetto | first2 = GM. | last3 = Antonini | first3 = G. | last4 = Giovannone | first4 = R. | last5 = Di Placido | first5 = M. | last6 = Magliocca | first6 = FM. | last7 = Di Silverio | first7 = A. | last8 = Gentile | first8 = V. | title = Incidental prostatic stromal tumor of uncertain malignant potential (STUMP): histopathological and immunohistochemical findings. | journal = Urologia | volume = 79 | issue = 1 | pages = 65-8 | month =  | year = 2012 | doi = 10.5301/RU.2012.9099 | PMID = 22388992 }}</ref>
*[[Leiomyosarcoma]].
*[[Leiomyosarcoma]].
*[[Rhabdomyosarcoma]].
*[[Rhabdomyosarcoma]].

Revision as of 23:58, 15 January 2015

Prostatic stromal tumour of uncertain malignant potential, abbreviated PSTUMP, is a rare lesion of the prostatic stroma which cannot be definitively classified as benign or malignant.

It may be abbreviated as STUMP;[1] an abbreviation used for a uterine lesion of uncertain malignant potential.

It is also known as prostatic stromal proliferation of uncertain malignant potential (abbreviated PSPUMP).[2]

General

  • Rare.

Microscopic

Features:

  • Overgrowth of spindle cells.

Note:

  • May be seen with glandular abnormalities.[3]

DDx:

IHC

Features:[1]

  • ER +ve.
  • PR +ve.
  • Desmin +ve/-ve.
  • CD34 +ve.

See also

References

  1. 1.0 1.1 1.2 De Berardinis, E.; Busetto, GM.; Antonini, G.; Giovannone, R.; Di Placido, M.; Magliocca, FM.; Di Silverio, A.; Gentile, V. (2012). "Incidental prostatic stromal tumor of uncertain malignant potential (STUMP): histopathological and immunohistochemical findings.". Urologia 79 (1): 65-8. doi:10.5301/RU.2012.9099. PMID 22388992.
  2. Gaudin, PB.; Rosai, J.; Epstein, JI. (Feb 1998). "Sarcomas and related proliferative lesions of specialized prostatic stroma: a clinicopathologic study of 22 cases.". Am J Surg Pathol 22 (2): 148-62. PMID 9500215.
  3. Nagar, M.; Epstein, JI. (Jun 2011). "Epithelial proliferations in prostatic stromal tumors of uncertain malignant potential (STUMP).". Am J Surg Pathol 35 (6): 898-903. doi:10.1097/PAS.0b013e318214f2f2. PMID 21572264.