Difference between revisions of "Cystic nephroma, adult type"
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==General== | ==General== | ||
*Rare. | *Rare.<ref name=pmid20427881>{{Cite journal | last1 = Mohanty | first1 = D. | last2 = Jain | first2 = BK. | last3 = Agrawal | first3 = V. | last4 = Gupta | first4 = A. | title = Cystic nephroma: a diagnostic dilemma. | journal = Saudi J Kidney Dis Transpl | volume = 21 | issue = 3 | pages = 518-20 | month = May | year = 2010 | doi = | PMID = 20427881 }}</ref> | ||
*Good prognosis.<ref name=pmid20427881/> | |||
==Gross== | ==Gross== | ||
Revision as of 06:03, 14 November 2014
Cystic nephroma is a rare kidney tumour.
Turbiner et al.[1] have suggested that cystic nephroma and mixed epithelial and stromal tumour (MEST) are one tumour; the lumping term is renal epithelial and stromal tumour (abbreviated REST).
General
Gross
- Bubble wrap-like appearance.
Image
Bubble wrap. (WC)
Microscopic
Features:
- Cysts lined by simple epithelium with hobnailing - key feature.
- Stroma has an ovarian look:
- Blue (basophilic).
- Spindle cells.
Notes:
- Parenchymal elements (e.g. glomueruli, tubules) are not found in the septa between the cysts.
Images
Cystic nephroma - low mag. (WC/Nephron)
Cystic nephroma - intermed. mag. (WC/Nephron)
IHC
Features:
- ER +ve.
- PR +ve.
- CD10 +ve.
See also
References
- ↑ Turbiner, J.; Amin, MB.; Humphrey, PA.; Srigley, JR.; De Leval, L.; Radhakrishnan, A.; Oliva, E. (Apr 2007). "Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term.". Am J Surg Pathol 31 (4): 489-500. doi:10.1097/PAS.0b013e31802bdd56. PMID 17414095.
- ↑ 2.0 2.1 Mohanty, D.; Jain, BK.; Agrawal, V.; Gupta, A. (May 2010). "Cystic nephroma: a diagnostic dilemma.". Saudi J Kidney Dis Transpl 21 (3): 518-20. PMID 20427881.