Difference between revisions of "Emperipolesis"
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Revision as of 03:14, 7 July 2014
Emperipolesis is an intact cell within another cell. The term is derived from em (inside), peri (around), and polemai (is wander about).
General
- Nonspecific finding seen in a number of conditions.
It is seen in:
- Rosai-Dorfman disease.
- Megakaryocytes.[1]
- Autoimmune hepatitis.
Microscopic
Features:
- Intact cell (e.g. lymphocyte, neutrophil) within a macrophage.
- Engulfed cell usually has a halo around it.
DDx:
- Cell overlap.
- Hemophagocytosis.
Images
Emperipolesis in Rosai-Dorfman disease. S100 immunostain.
Emperipolesis: Megakaryocyte containing a neutrophil. May-Grünwald Giemsa stain.
