Difference between revisions of "Endocervical adenocarcinoma in situ"

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(→‎IHC: +SO)
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*CEA +ve.
*CEA +ve.
*Vimentin -ve.
*Vimentin -ve.
==Sign out==
<pre>
UTERINE CERVIX, BIOPSY:
- HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (HSIL).
- ENDOCERVICAL ADENOCARCINOMA IN SITU (AIS).
- ACUTE AND CHRONIC INFLAMMATION.
COMMENT:
A p16 immunostain marks the full thickness of the squamous epithelium and is
strong. A Ki-67 immunostain marks increased numbers of superficial squamous cells.
The atypical endocervical epithelium (interpreted as AIS) is strongly p16 positive
and has an increased proliferative activity with Ki-67 staining.
</pre>
===Micro===
The atypical endocervical epithelium (interpreted as AIS) shows marked hyperchromasia, nuclear crowding and moderate nuclear atypia with a relatively abundant cytoplasm ( nucleus to cell size = 1:2 ).


==See also==
==See also==
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