Difference between revisions of "Histology artifacts"
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*Angulated pieces of tissue with punched-out missing fragments.<ref name=pmid2252429>{{cite journal |author=Landas SK, Bromley CM |title=Sponge artifact in biopsy specimens |journal=Arch. Pathol. Lab. Med. |volume=114 |issue=12 |pages=1285–7 |year=1990 |month=December |pmid=2252429 |doi= |url=}}</ref> | *Angulated pieces of tissue with punched-out missing fragments.<ref name=pmid2252429>{{cite journal |author=Landas SK, Bromley CM |title=Sponge artifact in biopsy specimens |journal=Arch. Pathol. Lab. Med. |volume=114 |issue=12 |pages=1285–7 |year=1990 |month=December |pmid=2252429 |doi= |url=}}</ref> | ||
*May result in little squares of tissue arranged in a regular pattern. | *May result in little squares of tissue arranged in a regular pattern. | ||
<gallery> | |||
Image: Endometrium with sponge artifact -- very low mag.jpg | Sponge artifact - very low mag. | |||
Image: Endometrium with sponge artifact -- low mag.jpg | Sponge artifact - low mag. | |||
Image: Endometrium with sponge artifact -- intermed mag.jpg | Sponge artifact - intermed. mag. | |||
</gallery> | |||
==Bubble artifact== | ==Bubble artifact== | ||
Revision as of 18:46, 9 March 2014
Histology artifacts are common.
Cautery artifact
Main article: Cautery artifact
Tissue fold
- Darker well demarcated line with apparent disruption of the architecture.
Tissue fold (center of image) in basal cell hyperplasia of the prostate.
Extensive tissue folding in a SSA.
Chatter artifact
- Fine parallel lines.
Chatter artifact in tubular adenoma.
Chatter artifact in complex endometrial hyperplasia.
Chatter artifact in TILs.
Tissue tearing
- Usually due to something intrinsic to the tissue that is hard, e.g. calcium.
Tearing due to a calcification.
Sponge artifact
- Angulated pieces of tissue with punched-out missing fragments.[1]
- May result in little squares of tissue arranged in a regular pattern.
Sponge artifact - very low mag.
Sponge artifact - low mag.
Sponge artifact - intermed. mag.
Bubble artifact
Large
- Large bubbles of air under the cover slip.
Coverslip artifact
Features:
- Black-grey lines - takes on the outline of the tissue beneath it.
- Above the plane-of-focus of the tissue - key feature.
Image:
See also
References
- ↑ Landas SK, Bromley CM (December 1990). "Sponge artifact in biopsy specimens". Arch. Pathol. Lab. Med. 114 (12): 1285–7. PMID 2252429.
- ↑ URL: http://www.statvetlab.com/diagnostic-resources/urinalysis. Accessed on: 3 March 2014.