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Soft tissue, left ear ("left ear keratosis"), excision - keratinaceous debris. | Soft tissue, left ear ("left ear keratosis"), excision - keratinaceous debris. | ||
==Cholesteatoma== | ==Cholesteatoma 1== | ||
===Microscopic description=== | ===Microscopic description=== | ||
The section shows lamellar keratin, abundant reactive histiocytes and multinucleated giant cells. Lymphocytes and plasma cells are present. There is dystrophic calcification. Fragments of bone are seen. | The section shows lamellar keratin, abundant reactive histiocytes and multinucleated giant cells. Lymphocytes and plasma cells are present. There is dystrophic calcification. Fragments of bone are seen. | ||
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===Final diagnosis=== | ===Final diagnosis=== | ||
Soft tissue, left ear ("left ear keratosis"), excision - keratinaceous debris and inflammation (consistent with cholesteatoma). | Soft tissue, left ear ("left ear keratosis"), excision - keratinaceous debris and inflammation (consistent with cholesteatoma). | ||
==Cholesteatoma 2== | |||
===Microscopic description=== | |||
The section shows lamellar keratin, a fragment of squamous epithelium and fragments of bone. No significant inflammation is identified. | |||
===Final diagnosis=== | |||
Soft tissue, left ear ("left ear keratosis"), excision - keratinaceous debris, squamous epithelium and bone (consistent with cholesteatoma). | |||
== Stoma == | |||
===Microscopic description=== | |||
The sections show mature squamous epithelium with parakeratosis, and colonic-type mucosa with focal lymphoid hyperplasia and reactive epithelial changes. The colonic-type mucosa has focal paneth cells, crypt dilation, mild crypt distortion and fibromuscular hyperplasia of the lamina propria and submucsoa. Foreign body-type granulomas (suture granulomas) are present in the lamina propria. Normal bowel wall smooth muscle is present. Ganglion cells are present. | |||
===Final diagnosis=== | |||
A. Sigmoid, excision - benign squamous epithelium and intestine wall with reactive colonic-type epithelium (consistent with stoma). | |||
== Foreskin == | |||
FORESKIN, EXCISION:<br> | |||
- STRATIFIED SQUAMOUS EPITHELIUM WITH KERATINIZATION, MILD FOCAL LYMPHOCYTIC INFILTRATE AND FOCAL ULCERATION.<br> | |||
- FIBROUS DERMAL TISSUE WITH PERIVASCULAR LYMPHOPLASMACYTIC INFILTRATE.<br> | |||
- NEGATIVE FOR MALIGNANCY. | |||
== Nail plate == | |||
<pre> | |||
PARTIAL NAIL PLATE, RIGHT THIRD TOE, SCISSOR EXCISION: | |||
- NAIL PLATE AND THIN LAYER OF KERATINIZED SQUAMOUS EPITHELIUM WITH | |||
PARAKERATOSIS AND FIBRIN. | |||
- NO APPARENT PIGMENT. | |||
- NO EVIDENCE OF MALIGNANCY. | |||
</pre> | |||
===Micro=== | |||
The sections show a paucicellular nail plate, and a thin layer of squamous epithelium with | |||
keratinization and partial retention of the nuclei (parakeratosis). There is also a small | |||
amount of fibrin. No pigmentation is apparent with Prussian blue and Fontana-Masson | |||
staining. No melanocytes are apparent. No nuclear atypia is apparent. No mitotic activity | |||
is identified. No microorganisms are apparent. No significant inflammation is apparent. | |||
== Another nail == | |||
<pre> | |||
GREAT TOENAIL, RIGHT, EXCISION: | |||
- NAIL PLATE AND THIN LAYER OF KERATINIZED SQUAMOUS EPITHELIUM. | |||
- SMALL CLUSTERS OF COCCI, FOCAL. | |||
- NO APPARENT FUNGAL ORGANISMS WITH PASF STAIN. | |||
- NO EVIDENCE OF MALIGNANCY. | |||
</pre> | |||
=Floppy eyelid syndrome= | |||
<pre> | |||
RIGHT EYE, SUPERIOR TARSAL CONJUNCTIVA, BIOPSY: | |||
- COMPATIBLE WITH CONJUNCTIVAL MUCOSA WITH FOCAL PARAKERATOSIS AND HYPERGRANULOSIS, | |||
RARE INTRAEPITHELIAL LYMPHOCYTES, DILATED SUPERFICIAL BLOOD VESSELS, AND A MILD | |||
PERIVASCULAR LYMPHOPLASMACYTIC INFILTRATE. | |||
- NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
== Bursa == | |||
A sample: | |||
<pre> | |||
RIGHT GREATER TROCHANTER, BURSA, RESECTION: | |||
- FIBROFATTY TISSUE CONSISTENT WITH BURSA. | |||
</pre> | |||
== Tonsilar cyst == | |||
<pre> | |||
LEFT TONSIL (QUERY RETENTION CYST), EXCISION: | |||
- SQUAMOUS MUCOSA WITH A MORPHOLOGICALLY BENIGN LYMPHOID AGGREGATE CONTAINING | |||
A BENIGN SQUAMOUS LINED CYST. | |||
- NEGATIVE FOR DYSPLASIA. | |||
- NO EVIDENCE OF MALIGNANCY. | |||
</pre> | |||