Difference between revisions of "Angiomyofibroblastoma"
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==General== | ==General== | ||
*Uncommon. | *Uncommon. | ||
*Similar lesions reported in males.<ref name=pmid24396463>{{Cite journal | last1 = Ding | first1 = G. | last2 = Yu | first2 = Y. | last3 = Jin | first3 = M. | last4 = Xu | first4 = J. | last5 = Zhang | first5 = Z. | title = Angiomyofibroblastoma-like tumor of the scrotum: A case report and literature review. | journal = Oncol Lett | volume = 7 | issue = 2 | pages = 435-438 | month = Feb | year = 2014 | doi = 10.3892/ol.2013.1741 | PMID = 24396463 }}</ref><ref>{{Cite journal | last1 = Butt | first1 = Z. | last2 = Slatnik | first2 = J. | last3 = Estey | first3 = EP. | title = Robotic assisted laparoscopic excision of a pelvic angiomyofibroblastoma-like tumor. | journal = Can J Urol | volume = 20 | issue = 6 | pages = 7067-9 | month = Dec | year = 2013 | doi = | PMID = 24331351 }}</ref> | |||
Clinical DDx: | Clinical DDx: | ||
*[[Bartholin cyst]]. | *[[Bartholin cyst]]. | ||
==Gross== | |||
*[[Vulvar lesion]]. | |||
==Microscopic== | ==Microscopic== | ||
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*[http://www.webpathology.com/image.asp?case=544&n=4 Angiomyofibroblastoma (webpathology.com)] | *[http://www.webpathology.com/image.asp?case=544&n=4 Angiomyofibroblastoma (webpathology.com)] | ||
*[http://www.webpathology.com/image.asp?n=5&Case=544 Angiomyofibroblastoma - high mag. (webpathology.com)]. | *[http://www.webpathology.com/image.asp?n=5&Case=544 Angiomyofibroblastoma - high mag. (webpathology.com)]. | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881198/figure/f2-ol-07-02-0435/ Angiomyofibroblastoma-like tumour of scrotum (nih.gov)].<ref name=pmid24396463/> | |||
==IHC== | |||
*SMA +ve. | |||
*S-100 -ve. | |||
*Actin -ve. | |||
*CD34 -ve. | |||
==See also== | ==See also== | ||
Revision as of 00:02, 17 February 2014
Angiomyofibroblastoma is rare uncommon soft tissue lesion of the vulva.
General
Clinical DDx:
Gross
Microscopic
Features:[3]
- Hypercellular zones and hypocellular edematous zones.
- Small blood vessels (~20 micrometers) - no large blood vessels - key feature.
- Myxoid stroma - key feature.
- Small stellate cell/spindle cells without significant nuclear atypia.
DDx:
- Aggressive angiomyxoma - less cellular, large blood vessels.
Images
www:
- Angiomyofibroblastoma (webpathology.com)
- Angiomyofibroblastoma - high mag. (webpathology.com).
- Angiomyofibroblastoma-like tumour of scrotum (nih.gov).[1]
IHC
- SMA +ve.
- S-100 -ve.
- Actin -ve.
- CD34 -ve.
See also
References
- ↑ 1.0 1.1 Ding, G.; Yu, Y.; Jin, M.; Xu, J.; Zhang, Z. (Feb 2014). "Angiomyofibroblastoma-like tumor of the scrotum: A case report and literature review.". Oncol Lett 7 (2): 435-438. doi:10.3892/ol.2013.1741. PMID 24396463.
- ↑ Butt, Z.; Slatnik, J.; Estey, EP. (Dec 2013). "Robotic assisted laparoscopic excision of a pelvic angiomyofibroblastoma-like tumor.". Can J Urol 20 (6): 7067-9. PMID 24331351.
- ↑ Fletcher, CD.; Tsang, WY.; Fisher, C.; Lee, KC.; Chan, JK. (Apr 1992). "Angiomyofibroblastoma of the vulva. A benign neoplasm distinct from aggressive angiomyxoma.". Am J Surg Pathol 16 (4): 373-82. PMID 1314521.