Difference between revisions of "Breast pathology"

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Breast pathology (view source)

Revision as of 18:31, 16 February 2014

1,816 bytes removed ,  18:31, 16 February 2014
→‎Microglandular adenosis: split out
(→‎Nipple adenoma: split out)
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:'''''Not''' to be confused with [[microglandular hyperplasia]]''.
:'''''Not''' to be confused with [[microglandular hyperplasia]]''.
*Abbreviated ''MGA''.
*Abbreviated ''MGA''.
===General===
{{Main|Microglandular adenosis}}
*Controversial thingy.
 
Management:
*Excision.
 
===Microscopic===
Features:<ref name=uscap_mga>URL: [http://www.uscap.org/site~/iap2006/slides08-4v.htm http://www.uscap.org/site~/iap2006/slides08-4v.htm]. Accessed on: 18 May 2011.</ref>
*Round glands lined by a single layer of cells.
*May extend into fat.
*Lack of desmoplastic stroma.
 
DDx:
*[[Tubular carcinoma]] - has apical snouts, desmoplasia among other things; see page by ''Collins''.<ref name=uscap_mga>URL: [http://www.uscap.org/site~/iap2006/slides08-4v.htm http://www.uscap.org/site~/iap2006/slides08-4v.htm]. Accessed on: 18 May 2011.</ref>
*[[Sclerosing adenosis]].
 
Images:
*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=1&s=20080802171452955&i=0&p=0 Microglandular adenosis (surgical pathologyatlas.com)].
*[http://webpathology.com/image.asp?n=1&Case=282 MGA - low mag. (webpathology.com)].
*[http://webpathology.com/image.asp?n=2&Case=282 MGA - high mag. (webpathology.com)].
*[http://www.breastpathology.info/Images/Benign/SclerAdenosis/mga1c_400.jpg MGA (breastpathology.info)].
*[http://www.breastpathology.info/sub-pages-iotw/2010/2.html MGA - several images (breastpathology.info)].
 
===IHC===
Features:<ref name=pmid8821958>{{Cite journal  | last1 = Joshi | first1 = MG. | last2 = Lee | first2 = AK. | last3 = Pedersen | first3 = CA. | last4 = Schnitt | first4 = S. | last5 = Camus | first5 = MG. | last6 = Hughes | first6 = KS. | title = The role of immunocytochemical markers in the differential diagnosis of proliferative and neoplastic lesions of the breast. | journal = Mod Pathol | volume = 9 | issue = 1 | pages = 57-62 | month = Jan | year = 1996 | doi =  | PMID = 8821958 }}</ref>
*S100 +ve.
*34BE12 +ve -- focal!
 
Others:
*EMA -ve.
**Tubular carcinoma usu. +ve.
*[[GCDFP-15]] -ve.<ref>{{Ref APBR|296 Q20}}</ref>
*Ki-67 <3%.


==Adenomyoepithelioma==
==Adenomyoepithelioma==
Michael
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