Difference between revisions of "Proton pump inhibitor effect"

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[[Image:Stomach with PPI effect -- very high mag.jpg|thumb|right|Stomach with PPI effect. [[H&E stain]].]]
[[Image:Stomach with PPI effect -- very high mag.jpg|thumb|right|250px|Stomach with PPI effect. [[H&E stain]].]]
'''Proton pump inhibitor effect''', abbreviated '''PPI effect''', is a change seen in the parietal cells of the [[stomach]] due to a drug in the proton pump inhibitor class.
'''Proton pump inhibitor effect''', abbreviated '''PPI effect''', is a change seen in the parietal cells of the [[stomach]] due to a drug in the proton pump inhibitor class.


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Features:<ref>{{Cite journal  | last1 = Driman | first1 = DK. | last2 = Wright | first2 = C. | last3 = Tougas | first3 = G. | last4 = Riddell | first4 = RH. | title = Omeprazole produces parietal cell hypertrophy and hyperplasia in humans. | journal = Dig Dis Sci | volume = 41 | issue = 10 | pages = 2039-47 | month = Oct | year = 1996 | doi =  | PMID = 8888719 }}</ref>
Features:<ref>{{Cite journal  | last1 = Driman | first1 = DK. | last2 = Wright | first2 = C. | last3 = Tougas | first3 = G. | last4 = Riddell | first4 = RH. | title = Omeprazole produces parietal cell hypertrophy and hyperplasia in humans. | journal = Dig Dis Sci | volume = 41 | issue = 10 | pages = 2039-47 | month = Oct | year = 1996 | doi =  | PMID = 8888719 }}</ref>
*Parietal cell enlargement - '''key feature'''.
*Parietal cell enlargement - '''key feature'''.
**Parietal cells typically bulge into the lumen.


===Images===
===Images===
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