Difference between revisions of "Gastric xanthoma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = | |||
| Micro = gastric lamina propria with lipid-laden macrophages | |||
| Subtypes = | |||
| LMDDx = [[signet ring cell carcinoma]], [[Whipple disease]], [[MAI]] infection | |||
| Stains = | |||
| IHC = CD68 +ve, AE1/AE3 -ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = yellowish nodule or plaque - usu. lesser curvature | |||
| Grossing = | |||
| Site = [[stomach]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Gastric xanthoma''', abbreviated ''GX'', is an uncommon benign lesion of the stomach. | '''Gastric xanthoma''', abbreviated ''GX'', is an uncommon benign lesion of the stomach. | ||
Revision as of 04:04, 22 December 2013
| Gastric xanthoma | |
|---|---|
| Diagnosis in short | |
|
| |
| LM | gastric lamina propria with lipid-laden macrophages |
| LM DDx | signet ring cell carcinoma, Whipple disease, MAI infection |
| IHC | CD68 +ve, AE1/AE3 -ve |
| Gross | yellowish nodule or plaque - usu. lesser curvature |
| Site | stomach |
|
| |
| Prevalence | uncommon |
| Prognosis | benign |
Gastric xanthoma, abbreviated GX, is an uncommon benign lesion of the stomach.
It is also known as xanthelasma and stomach lipidosis.
General
- Uncommon.
- Benign.
Gross/endoscopic
Microscopic
Features:[1]
- Collections of gastric lamina propria with lipid-laden macrophages.
DDx:
- Signet ring cell carcinoma.[2]
- Whipple disease.
- MAC infection.
Images
Xanthoma. (WC)
www:
IHC
- CD68 +ve.
- Panker (AE1/AE3) -ve.
- To exclude carcinoma.
See also
References
- ↑ 1.0 1.1 Iacobuzio-Donahue, Christine A.; Montgomery, Elizabeth A. (2005). Gastrointestinal and Liver Pathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 111. ISBN 978-0443066573.
- ↑ 2.0 2.1 Drude, RB.; Balart, LA.; Herrington, JP.; Beckman, EN.; Burns, TW. (Jun 1982). "Gastric xanthoma: histologic similarity to signet ring cell carcinoma.". J Clin Gastroenterol 4 (3): 217-21. PMID 6284833.