Difference between revisions of "Phosphaturic mesenchymal tumour, mixed connective tissue type"

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'''Phosphaturic mesenchymal tumor''' is a rare tumour.
'''Phosphaturic mesenchymal tumour, mixed connective tissue type''', abbreviated '''PMTMCT''', is a rare tumour.  
 
One type is the '''phosphaturic mesenchymal tumour, mixed connective tissue type''', abbreviated '''PMTMCT'''.


==General==
==General==

Revision as of 11:40, 19 August 2013

Phosphaturic mesenchymal tumour, mixed connective tissue type
Diagnosis in short
Site soft tissue, bone

Blood work low serum phosphate

Phosphaturic mesenchymal tumour, mixed connective tissue type, abbreviated PMTMCT, is a rare tumour.

General

  • Extremely rare.
  • Hypophosphatemia.[1]
  • Most common cause of oncogenic osteomalacia (tumour-induced osteomalacia).[2]

Gross

  • Soft tissue or bone.[3]
  • Often small - thus hard to identify.[4]

Microscopic

Features:[2]

  • Spindle cells without atypia in an eosinophilic matrix.
  • Osteoclast-type giant cells.
  • +/-Calcifications.

Image:

References

  1. Papierska, L.; Ćwikła, JB.; Misiorowski, W.; Rabijewski, M.; Sikora, K.; Wanyura, H. (2013). "Unusual case of phosphaturic mesenchymal tumor.". Pol Arch Med Wewn 123 (5): 255-6. PMID 23722193.
  2. 2.0 2.1 William, J.; Laskin, W.; Nayar, R.; De Frias, D. (Aug 2012). "Diagnosis of phosphaturic mesenchymal tumor (mixed connective tissue type) by cytopathology.". Diagn Cytopathol 40 Suppl 2: E109-13. doi:10.1002/dc.21647. PMID 22927293.
  3. Jiang, Y.; Xia, WB.; Xing, XP.; Silva, BC.; Li, M.; Wang, O.; Zhang, HB.; Li, F. et al. (Sep 2012). "Tumor-induced osteomalacia: an important cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature.". J Bone Miner Res 27 (9): 1967-75. doi:10.1002/jbmr.1642. PMID 22532501.
  4. Ledford, CK.; Zelenski, NA.; Cardona, DM.; Brigman, BE.; Eward, WC. (Jul 2013). "The Phosphaturic Mesenchymal Tumor: Why is Definitive Diagnosis and Curative Surgery Often Delayed?". Clin Orthop Relat Res. doi:10.1007/s11999-013-3178-1. PMID 23868423.
  5. Woo, VL.; Landesberg, R.; Imel, EA.; Singer, SR.; Folpe, AL.; Econs, MJ.; Kim, T.; Harik, LR. et al. (Dec 2009). "Phosphaturic mesenchymal tumor, mixed connective tissue variant, of the mandible: report of a case and review of the literature.". Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108 (6): 925-32. doi:10.1016/j.tripleo.2009.07.005. PMID 19828339.