Difference between revisions of "Ovary"
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The '''ovary''' has a wealth of [[pathology]]. It has benign tumours and malignant ones. It is a significant part of [[gynecologic pathology]]. | The '''ovary''' has a wealth of [[pathology]]. It has benign tumours and malignant ones. It is a significant part of [[gynecologic pathology]]. | ||
=Normal ovary= | |||
*Corpora albicans - pale/white body with lobulated contour. | *Corpora albicans - pale/white body with lobulated contour. | ||
**Involuted corpus luteum. | **Involuted corpus luteum. | ||
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*[http://commons.wikimedia.org/wiki/File:Corpus_albicans.JPG Corpus albicans (WC)]. | *[http://commons.wikimedia.org/wiki/File:Corpus_albicans.JPG Corpus albicans (WC)]. | ||
=Cysts - overview= | |||
General: | General: | ||
*Very common. | *Very common. | ||
| Line 40: | Line 40: | ||
*Image: [http://internetattitude.com/bioimage/OldSlides/bio231histo800x600/Mesothelium%20Simple%20Squamous%20x440.JPG mesothelium] - internetattitude.com. | *Image: [http://internetattitude.com/bioimage/OldSlides/bio231histo800x600/Mesothelium%20Simple%20Squamous%20x440.JPG mesothelium] - internetattitude.com. | ||
=Specific benign diagnoses= | |||
==Endometriosis== | ==Endometriosis== | ||
{{main|Endometriosis}} | {{main|Endometriosis}} | ||
==Benign mesothelial inclusion cyst== | ==Benign mesothelial inclusion cyst== | ||
| Line 113: | Line 110: | ||
*[http://www.webpathology.com/image.asp?n=2&Case=522 Pregnancy luteoma - high mag. (webpathology.com)]. | *[http://www.webpathology.com/image.asp?n=2&Case=522 Pregnancy luteoma - high mag. (webpathology.com)]. | ||
==See also | =Ovarian tumours= | ||
{{main|Ovarian tumours}} | |||
For a ''very'' brief overview of gynecologic tumours see: ''[[Gynecologic pathology]]''. | |||
=See also= | |||
*[[Gynecologic pathology]]. | *[[Gynecologic pathology]]. | ||
*[[Testis]]. | *[[Testis]]. | ||
=References= | |||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Gynecologic pathology]] | [[Category:Gynecologic pathology]] | ||
Revision as of 20:12, 14 March 2013
The ovary has a wealth of pathology. It has benign tumours and malignant ones. It is a significant part of gynecologic pathology.
Normal ovary
- Corpora albicans - pale/white body with lobulated contour.
- Involuted corpus luteum.
- Not seen pre-pubertal.
- Number increase with age.
- Ovarian follicles.
- Stroma - hyperchromatic - spindle morphology, whorling.
- If the cells have a round morphology... think about endometriosis.
Images:
Cysts - overview
General:
- Very common.
Most common:
- Serous cystadenoma.
- Usually uniloculated.
- Morphology: ciliated, columnar.
- Mucinous cystadenoma.
- Usually multiloculated.[1]
- Memory device: multiloculated = mucinous.
- Usually multiloculated.[1]
- Endometrioma (see endometriosis).
- Simple cyst.
- Cancerous cyst (see ovarian cancer).
Notes
- Epithelium is often lost in processing - may make interpretation challenging
- Ovarian surface epithelium (previously call germinal epithelium) - covers the ovary
Ovarian surface vs. mesothelium:
- Image: ovarian surface epithelium - endojournals.org.
- Image: mesothelium - internetattitude.com.
Specific benign diagnoses
Endometriosis
Main article: Endometriosis
Benign mesothelial inclusion cyst
- AKA mesothelial inclusion cyst.
- AKA peritoneal inclusion cyst.[citation needed]
- AKA cortical inclusion cyst.[4][citation needed]
General
- May be found incidentally, e.g. during C-section.
Epidemiology:
- Associated with previous surgery.
Gross
Microscopic
Features:
- Benign mesothelium.
- Single layer of squamoid or cuboid mesothelial cells.[6]
DDx:
Image:
IHC
- CK +ve, calretinin +ve.[6]
Sign out
OVARY, LEFT, BIOPSY: - BENIGN CORTICAL INCLUSION CYST.
Pregnancy luteoma
General
- Tumour of pregnancy.
- Benign.
- Regress after pregnancy; thus, conservative management.[8]
Clinical:
- Increased serum testosterone.[9]
Gross
- Solid.
- Yellow.
Images:
Microscopic
Features:
- Sheets of cells.
- Cells with eosinophilic cytoplasm, round nuclei and prominent nucleoli.
DDx:
Images:
Ovarian tumours
Main article: Ovarian tumours
For a very brief overview of gynecologic tumours see: Gynecologic pathology.
See also
References
- ↑ IAV. 6 February 2009.
- ↑ Auersperg N, Wong AS, Choi KC, Kang SK, Leung PC (April 2001). "Ovarian surface epithelium: biology, endocrinology, and pathology". Endocr. Rev. 22 (2): 255–88. PMID 11294827. http://edrv.endojournals.org/cgi/pmidlookup?view=long&pmid=11294827.
- ↑ ALS. 5 February 2009.
- ↑ Feeley, KM.; Wells, M. (Feb 2001). "Precursor lesions of ovarian epithelial malignancy.". Histopathology 38 (2): 87-95. PMID 11207821.
- ↑ GAG 26 Feb 2009.
- ↑ 6.0 6.1 6.2 Urbanczyk K, Skotniczny K, Kucinski J, Friediger J (2005). "Mesothelial inclusion cysts (so-called benign cystic mesothelioma)--a clinicopathological analysis of six cases". Pol J Pathol 56 (2): 81-7. PMID 16092670.
- ↑ Asch, E.; Levine, D.; Kim, Y.; Hecht, JL. (Mar 2008). "Histologic, surgical, and imaging correlations of adnexal masses.". J Ultrasound Med 27 (3): 327-42. PMID 18314510.
- ↑ Masarie, K.; Katz, V.; Balderston, K. (Sep 2010). "Pregnancy luteomas: clinical presentations and management strategies.". Obstet Gynecol Surv 65 (9): 575-82. doi:10.1097/OGX.0b013e3181f8c41d. PMID 21144088.
- ↑ Kao, HW.; Wu, CJ.; Chung, KT.; Wang, SR.; Chen, CY.. "MR imaging of pregnancy luteoma: a case report and correlation with the clinical features.". Korean J Radiol 6 (1): 44-6. PMID 15782020.