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Difference between revisions of "Langerhans cell histiocytosis"
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| Multifocal multisystem Langerhans cell histiocytosis | | Multifocal multisystem Langerhans cell histiocytosis | ||
| Letterer-Siwe disease | | Letterer-Siwe disease | ||
| natural history 2 year survival, 50% five year survival with treatment | | outcome dependent on organ involved,<ref name=pmid21351807>{{Cite journal | last1 = Minkov | first1 = M. | title = Multisystem Langerhans cell histiocytosis in children: current treatment and future directions. | journal = Paediatr Drugs | volume = 13 | issue = 2 | pages = 75-86 | month = Apr | year = 2011 | doi = 10.2165/11538540-000000000-00000 | PMID = 21351807 }}</ref> natural history 2 year survival, 50% five year survival with treatment | ||
| children | | usu. children < 2 years old, rarely adults<ref name=pmid22470214>{{Cite journal | last1 = Garg | first1 = A. | last2 = Kumar | first2 = P. | title = Multisystem Langerhans cell histiocytosis in adult. | journal = Indian J Dermatol | volume = 57 | issue = 1 | pages = 58-60 | month = Jan | year = 2012 | doi = 10.4103/0019-5154.92683 | PMID = 22470214 }}</ref> | ||
| multiple systems (skin, spleen, liver, lung, bone marrow) | | multiple systems (skin, spleen, liver, lung, bone marrow) | ||
| genetic | | genetic | ||