Difference between revisions of "Anemia"
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*Autoimmune - leads to loss of parietal cells. | *Autoimmune - leads to loss of parietal cells. | ||
**Parietal cells produce ''intrinsic factor'' (important for vitamin B12 absorption) and ''hydrogen chloride''. | **Parietal cells produce ''intrinsic factor'' (important for vitamin B12 absorption) and ''hydrogen chloride''. | ||
Diagnosis - serology for antibodies to:<ref name=pmid12643357>{{Cite journal | last1 = Oh | first1 = R. | last2 = Brown | first2 = DL. | title = Vitamin B12 deficiency. | journal = Am Fam Physician | volume = 67 | issue = 5 | pages = 979-86 | month = Mar | year = 2003 | doi = | PMID = 12643357 }}</ref> | |||
*Parietal cell. | |||
*Iintrinsic factor. | |||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Loss of parietal cells. | *Loss of parietal cells. | ||
=See also= | =See also= | ||
*[[Sickle cell anemia]]. | *[[Sickle cell anemia]]. | ||
Revision as of 20:28, 20 April 2012
Anemia is low hemoglobin.
There is a long list of causes for anemia. Usually, anemia is grouped by RBC cell size, mean corpuscular volume (MCV).
Classifications
| Anemia | |||||||||||||||||||||||||||||||||||
| Macrocytic anemia (MCV>100) | Normocytic anemia (MCV 80–100) | Microcytic anemia (MCV<80) | |||||||||||||||||||||||||||||||||
Microcytic anemia
Mnemonic TAILS:[1]
- Thalassemia.
- Anemia of chronic diesease.
- Iron deficiency anemia.
- Lead toxicity.
- Sideroblastic anemia.
Macrocytic anemia
Mnemonic Few Big RBCs May Lead To Palor:
- Folate deficiency.
- Vitamin B12 deficiency.
- Rx.
- Myelodysplastic syndromes.
- Liver disease (cirrhosis).
- Thyroid disease (hypothyroidism).
- Post-splenectomy.
Specific types of anemia
Pernicious anemia
General
- Macrocytic anemia.
Etiology:
- Autoimmune - leads to loss of parietal cells.
- Parietal cells produce intrinsic factor (important for vitamin B12 absorption) and hydrogen chloride.
Diagnosis - serology for antibodies to:[2]
- Parietal cell.
- Iintrinsic factor.
Microscopic
Features:
- Loss of parietal cells.
See also
References
- ↑ URL: http://www.step2review.com/content/sub_cat.php?cat_id=487__Microcytic_Anemia. Accessed on: 12 May 2011.
- ↑ Oh, R.; Brown, DL. (Mar 2003). "Vitamin B12 deficiency.". Am Fam Physician 67 (5): 979-86. PMID 12643357.