Difference between revisions of "Sjögren syndrome"
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Revision as of 04:29, 24 March 2012
Sjögren syndrome, also Sjögren disease, is a disease that keeps rheumatologists busy. Sjögren is also spelled Sjoegren and Sjogren.
General
Clinical - classically:
- Women in 50s.
- Dry mouth (xerostomia).
- Dry eyes (xerophthalmia).
Blood work:[1]
- ANA +ve.
- Anti-SSA (Ro) +ve.
- Anti-SSB (La) +ve.
Microscopic
Features (salivary gland):[1]
- Lymphocytic infiltration - key feature.
- +/-Atrophy of salivary gland.
- +/-Fibrosis.
DDx: