Difference between revisions of "Syphilis"
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*Classically affects the [[testis]] before the epididymis.<ref name=Ref_WMSP364>{{Ref WMSP|364}}</ref> | *Classically affects the [[testis]] before the epididymis.<ref name=Ref_WMSP364>{{Ref WMSP|364}}</ref> | ||
*Considered one of the [[TORCH infections]]. | *Considered one of the [[TORCH infections]]. | ||
==Gross== | |||
Aorta: | |||
*Wrinkled intimal surface - "tree bark" appearance.<ref>{{Ref AoGP|80}}</ref> | |||
==Microscopic== | ==Microscopic== | ||
Revision as of 01:10, 28 February 2012
Syphilis is the infectious disease caused by Treponema pallidum.
General
- Classically affects the testis before the epididymis.[1]
- Considered one of the TORCH infections.
Gross
Aorta:
- Wrinkled intimal surface - "tree bark" appearance.[2]
Microscopic
Features:
- Plasma cells - key feature.[3]
- Spirochetes - diagnostic.
- +/-Granulomas[4] - gumma - in the tertiary phase.[5]
Useful stains:
Image: Dieterle stain - T. pallidum (WC).
See also
References
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 364. ISBN 978-0781765275.
- ↑ Rose, Alan G. (2008). Atlas of Gross Pathology with Histologic Correlation (1st ed.). Cambridge University Press. pp. 80. ISBN 978-0521868792.
- ↑ Brinster, NK. (Nov 2008). "Dermatopathology for the surgical pathologist: a pattern-based approach to the diagnosis of inflammatory skin disorders (part II).". Adv Anat Pathol 15 (6): 350-69. doi:10.1097/PAP.0b013e31818b1ac6. PMID 18948765.
- ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 47. ISBN 978-1416054542.
- ↑ URL: http://pediatrics.aappublications.org/cgi/content/full/104/1/e4. Accessed on: 17 November 2010.