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Difference between revisions of "Testis"
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→Seminoma: mroe
m (→Microscopic) |
(→Seminoma: mroe) |
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| Line 205: | Line 205: | ||
Clinical: | Clinical: | ||
*Elevated serum LDH. | *Elevated serum LDH. | ||
*Normal serum alpha fetoprotein. | |||
*Usually normal beta-hCG. | |||
===Epidemiology & etiology=== | ===Epidemiology & etiology=== | ||
*Arises from ''intratubular germ cell neoplasia'' (ITGCN). | *Arises from ''intratubular germ cell neoplasia'' (ITGCN). | ||
=== | ===Microsopic=== | ||
Features: | Features: | ||
*Cells with fried egg appearance. | *Cells with fried egg appearance. | ||
| Line 229: | Line 231: | ||
DDx: | DDx: | ||
*Mixed germ cell tumour. | *[[Mixed germ cell tumour]]. | ||
*Solid variant of yolk sac tumour. | *Solid variant of [[yolk sac tumour]]. | ||
**Lacks fibrous septae and lymphocytes.<ref>URL: [http://webpathology.com/image.asp?case=34&n=8 http://webpathology.com/image.asp?case=34&n=8]. Accessed on: March 8, 2010.</ref> | **Lacks fibrous septae and lymphocytes.<ref>URL: [http://webpathology.com/image.asp?case=34&n=8 http://webpathology.com/image.asp?case=34&n=8]. Accessed on: March 8, 2010.</ref> | ||
*[[Choriocarcinoma]] - esp. if (multinucleated) syncytiotrophoblasts are present. | |||
*Granulomatous orchitis - if [[granuloma]]s are present. | |||
===IHC=== | ===IHC=== | ||