Difference between revisions of "Diffuse lung diseases"

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885 bytes added ,  23:18, 10 December 2011
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==Asbestosis==
==Asbestosis==
===General===
===General===
*Important to diagnose... asbestosis = compensation.
Definition:
*Interstitial lung disease due to asbestos exposure.<ref name=Ref_PCPBoD8_375>{{Ref PCPBoD8|375}}</ref>
**Important to diagnose... asbestosis = compensation.
 
Conditions associated with asbestos exposure (mnemonic ''PALM''):<ref name=Ref_PCPBoD8_375>{{Ref PCPBoD8|375}}</ref>
*Pleural plaques.
*Asbestosis.
*[[Malignant mesothelioma]].
*[[Lung carcinoma]].
 
Possible association with asbestos exposure:
*[[Gestational trophoblastic disease]].<ref name=pmid19900938>{{Cite journal  | last1 = Reid | first1 = A. | last2 = Heyworth | first2 = J. | last3 = de Klerk | first3 = N. | last4 = Musk | first4 = AW. | title = Asbestos exposure and gestational trophoblastic disease: a hypothesis. | journal = Cancer Epidemiol Biomarkers Prev | volume = 18 | issue = 11 | pages = 2895-8 | month = Nov | year = 2009 | doi = 10.1158/1055-9965.EPI-09-0731 | PMID = 19900938 }}</ref>


===Microscopic===
===Microscopic===
*Histologic appearance as for UIP -- plus ''ferruginous bodies''.
Features:
**Segmented twirling batton with long slender fibre within.
*Histologic appearance as for [[usual interstitial pneumonia]] (UIP).
*''Ferruginous bodies'' - '''key feature'''.
**Segmented twirling baton with long slender fibre within.


Image(s):
Images:
*[http://commons.wikimedia.org/wiki/File:Ferruginous_body.jpg Ferruginous bodies (WC)].
*[http://commons.wikimedia.org/wiki/File:Ferruginous_body.jpg Ferruginous bodies (WC)].
*[http://commons.wikimedia.org/wiki/File:Asbestosis_high_mag.jpg Asbestosis (WC)].
*[http://commons.wikimedia.org/wiki/File:Asbestosis_high_mag.jpg Asbestosis (WC)].
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