Difference between revisions of "Transurethral resection of bladder tumour grossing"

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==Protocol==
==Protocol==
*Weight specimen.
Specimen:
*Submit in total for TUR specimens up to 10 grams.<ref name=pmid34926567>{{cite journal |authors=Mazzucchelli R, Marzioni D, Tossetta G, Pepi L, Montironi R |title=Bladder Cancer Sample Handling and Reporting: Pathologist's Point of View |journal=Front Surg |volume=8 |issue= |pages=754741 |date=2021 |pmid=34926567 |pmc=8674620 |doi=10.3389/fsurg.2021.754741 |url=}}</ref>
*Weight ___ grams.
*If tumour recognized, submit 1 block per cm of tumour.<ref name=pmid34926567/>
*Dimensions (in aggregate): ___ x ___ x ___ cm.
*Number of fragments: [1-6 / multiple (>6)].
*Appearance: [tan-gray / yellow / orange].
*Consistency: [rubbery / firm].
*Other: [none / hemorrhagic appearance / necrotic appearing].
[Submitted in total/Representative sections submitted] in block(s) ___. †


Notes:
*Recommendations vary on what to do with large TUR specimens - see ''[[Transurethral_resection_of_bladder_tumour_grossing#Alternate_approaches|alternate approaches]]'' section.
† Submit 15 blocks for initial assessment - if not muscle invasive: submit more tissue.


===Protocol notes===
===Protocol notes===
*The ''European Association of Urology'' recommends submitting separately the exophytic part of the tumour and tumour base in separate containers.<ref name=pmid34926567/>
*The ''European Association of Urology'' (''EAU'') recommends submitting separately the exophytic part of the tumour and tumour base in separate containers.<ref name=pmid34926567/>
**If the specimen is submitted as per ''EAU'' recommendations, submission of the tumour base may be sufficient for staging purposes.


====Staging====
====Staging====
Line 20: Line 30:


===Alternate approaches===
===Alternate approaches===
Mazzuccheli ''et al.'' suggests:<ref name=pmid34926567>{{cite journal |authors=Mazzucchelli R, Marzioni D, Tossetta G, Pepi L, Montironi R |title=Bladder Cancer Sample Handling and Reporting: Pathologist's Point of View |journal=Front Surg |volume=8 |issue= |pages=754741 |date=2021 |pmid=34926567 |pmc=8674620 |doi=10.3389/fsurg.2021.754741 |url=}}</ref>
*EIT for TUR specimens up to 10 grams.
*If tumour can be identified at gross: submit 1 block per cm of tumour + some additional tumour if >10 blocks.<ref name=pmid34926567/>
University of Chicago suggests:<ref>URL: [https://voices.uchicago.edu/grosspathology/gu-renal/bladder-turbt/ https://voices.uchicago.edu/grosspathology/gu-renal/bladder-turbt/]. Accessed on: 2024 June 10.</ref>
*Submit in total.
UCLA Health suggests:<ref>URL: [https://www.uclahealth.org/sites/default/files/documents/59/transurethral-resection-bladder-tumor-turbt-022223.pdf https://www.uclahealth.org/sites/default/files/documents/59/transurethral-resection-bladder-tumor-turbt-022223.pdf]. Accessed on: 2024 June 10.</ref>
*Submit 20 blocks.  If tissue remains consult with the pathologist.
==See also==
==See also==
*[[Urothelial carcinoma]].
*[[Urothelial carcinoma]].

Revision as of 22:43, 10 June 2024

This article deals with transurethral resection of bladder tumour grossing, also TURBT grossing and TUR specimens.

Introduction

TURBT specimens are common urologic pathology specimens.

Specimen opening

  • Not applicable.

Protocol

Specimen:

  • Weight ___ grams.
  • Dimensions (in aggregate): ___ x ___ x ___ cm.
  • Number of fragments: [1-6 / multiple (>6)].
  • Appearance: [tan-gray / yellow / orange].
  • Consistency: [rubbery / firm].
  • Other: [none / hemorrhagic appearance / necrotic appearing].

[Submitted in total/Representative sections submitted] in block(s) ___. †

Notes:

† Submit 15 blocks for initial assessment - if not muscle invasive: submit more tissue.

Protocol notes

  • The European Association of Urology (EAU) recommends submitting separately the exophytic part of the tumour and tumour base in separate containers.[1]
    • If the specimen is submitted as per EAU recommendations, submission of the tumour base may be sufficient for staging purposes.

Staging

  • Not done at time of gross.

Alternate approaches

Mazzuccheli et al. suggests:[1]

  • EIT for TUR specimens up to 10 grams.
  • If tumour can be identified at gross: submit 1 block per cm of tumour + some additional tumour if >10 blocks.[1]

University of Chicago suggests:[2]

  • Submit in total.

UCLA Health suggests:[3]

  • Submit 20 blocks. If tissue remains consult with the pathologist.

See also

Related protocols

References

  1. ↑ 1.0 1.1 1.2 Mazzucchelli R, Marzioni D, Tossetta G, Pepi L, Montironi R (2021). "Bladder Cancer Sample Handling and Reporting: Pathologist's Point of View". Front Surg 8: 754741. doi:10.3389/fsurg.2021.754741. PMC 8674620. PMID 34926567. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674620/.
  2. ↑ URL: https://voices.uchicago.edu/grosspathology/gu-renal/bladder-turbt/. Accessed on: 2024 June 10.
  3. ↑ URL: https://www.uclahealth.org/sites/default/files/documents/59/transurethral-resection-bladder-tumor-turbt-022223.pdf. Accessed on: 2024 June 10.
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