View source for Spread through air spaces

'''Spread through air spaces''', abbreviated '''STATS''', is a poor prognosticator in [[lung cancer]].

==Definition==
It is defined as tumour that is in the air space and some distance from the main tumour.<ref name=pmid33199839>{{cite journal |authors=Han YB, Kim H, Mino-Kenudson M, Cho S, Kwon HJ, Lee KR, Kwon S, Lee J, Kim K, Jheon S, Lee CT, Lee JS, Kook W, Chung JH |title=Tumor spread through air spaces (STAS): prognostic significance of grading in non-small cell lung cancer |journal=Mod Pathol |volume=34 |issue=3 |pages=549–561 |date=March 2021 |pmid=33199839 |doi=10.1038/s41379-020-00709-2 |url=}}</ref>

==Grading of STATS==
A study by Han ''el al.'' divided STATS into two groups:
*Grade I: < 2.5 mm from the tumour.
*Grade II: >= 2.5 mm from the tumour.

Grade II STATS is a poor prognosticator.<ref name=pmid33199839/> 

==See also==
*[[Lung cancer staging]].
*[[Worst pattern of invasion]].

==References==
{{Reflist|1}}

[[Category:Pulmonary pathology]]