Two vessel umbilical cord

From Libre Pathology
(Redirected from Two vessel cord)
Jump to navigation Jump to search

Two vessel umbilical cord, also two vessel cord and single umbilical artery, is an abnormality seen in placental pathology.

General

Associations:

  • Associated with congenital abnormalities, esp. cardiac - key point.[1]
    • Thought to be an acquired defect (as prevalence is lower early in gestation).
  • May be seen in association of other cord abnormalities (e.g. marginal insertion, velamentous insertion).
  • In apparently well (liveborn) infants it is associated with (occult) renal abnormalities, specifically vesico-ureteric reflux; there is no evidence for other abnormalities.[2]
  • Associated with maternal diabetes.[3]

Gross

  • Two vessels in the umbilical cord.

Microscopic

Features:

  • Two vessels in the umbilical cord - one artery and one vein.

Image

www:

Sign out

PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CAESAREAN SECTION:
- TWO VESSEL UMBILICAL CORD, NEGATIVE FOR INFLAMMATION.
- FETAL MEMBRANES WITHIN NORMAL LIMITS.
- PLACENTAL DISC WITH THIRD TRIMESTER VILLI WITHOUT APPARENT PATHOLOGY.

With meconium

PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CAESAREAN SECTION:
- TWO VESSEL UMBILICAL CORD, NEGATIVE FOR INFLAMMATION.
- FETAL MEMBRANES WITH FOCAL PIGMENTED CELLS CONSISTENT WITH MECONIUM,
  NEGATIVE FOR APPARENT CHORIOAMNIONITIS.
- PLACENTAL DISC WITH THIRD TRIMESTER VILLI WITHOUT APPARENT PATHOLOGY.

See also

References

  1. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 464. ISBN 978-0781765275.
  2. Srinivasan R, Arora RS (January 2005). "Do well infants born with an isolated single umbilical artery need investigation?". Arch. Dis. Child. 90 (1): 100–1. doi:10.1136/adc.2004.062372. PMC 1720078. PMID 15613529. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1720078/.
  3. Lilja M (July 1994). "Infants with single umbilical artery studied in a national registry. 3: A case control study of risk factors". Paediatr Perinat Epidemiol 8 (3): 325–33. PMID 7997408.
  4. URL: http://www.glowm.com/?p=glowm.cml/section_view&articleid=151. Accessed on: 8 January 2011.